ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-26.PDB
Scoring matrix: FUS1_1OV32-26_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 16.35
Foldx random average score for Saccharomyces cerevisiae: 11.783

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1459163
Proteins after disorder filtering: 4401
 Total fragments: 67660
Proteins after pattern filtering: 2146
 Total fragments: 13892
Proteins after MINT filtering: 22
 Total fragments: 229


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

16.35

1.39

0.00

Best peptides

WRRRRRYPF

0.00

-4.93

-6.32

         
Interactors      
P11710

SKPLPLTPN

10.49

-2.09

-3.48

PLTPNSKYN

10.74

-1.20

-2.59

PLPLTPNSK

10.98

-0.93

-2.32

P36119

TRPTVQPSN

10.02

-1.07

-2.46

TTRPTVQPS

10.32

-0.45

-1.84

P53046

STPPTPKSA

11.40

-1.19

-2.58

NQLSTPPTP

11.45

-1.31

-2.70

P24583

PLPPQPRKH

9.77

-3.07

-4.46

LPPQPRKHD

10.29

-1.04

-2.43

RANAPLPPQ

10.53

-2.65

-4.04

P53947

FNPIQDPFT

9.48

-0.95

-2.34

SPFNPIQDP

10.91

-3.11

-4.50

PFNPIQDPF

11.62

-1.09

-2.48

P34250

HSKKPSNPP

8.54

-1.58

-2.97

LYPKEPPAR

9.59

-2.46

-3.85

EPKPAYVPP

10.07

-1.36

-2.75

Q03466

VPMAPDTFN

9.63

-1.51

-2.90

SVPMAPDTF

10.77

-1.47

-2.86

Q12280

PLRPQSSSK

9.63

-1.24

-2.63

SGSPSKPGN

9.90

-2.26

-3.65

VTPPLRPQS

9.93

-3.46

-4.85

P39732

STRHPSIAP

9.08

-3.66

-5.05

PSIAPPSKL

10.37

-0.73

-2.12

SSRSPSVSP

10.48

-1.64

-3.03

P40091

WDPSSPSSV

10.32

0.80

-0.59

QNPSHPHHN

10.62

-0.70

-2.09

PSHPHHNSR

11.22

-1.85

-3.24

P40450

SSPKLFPRL

7.80

-1.88

-3.27

PPPPPPPPL

8.49

-3.15

-4.54

LPPPPPPPP

9.26

-3.10

-4.49

P25376

NDRPSSQPH

8.83

-1.88

-3.27

DRPSSQPHL

10.77

-1.07

-2.46

P41832

PPPPPPPPM

8.26

-3.46

-4.85

GVIPPAPPM

8.58

-3.03

-4.42

VIPPAPPMM

9.22

-2.90

-4.29

P31374

NISPERPSF

7.22

-2.82

-4.21

PERPSFRQP

7.98

-3.25

-4.64

FRKTKPPPP

7.99

-4.08

-5.47

P32917

QSRFPPYSP

7.15

-4.27

-5.66

PYSPLLPPF

8.50

-4.46

-5.85

NIPPKVAPF

8.87

-2.99

-4.38

P40020

FDRPPPLTP

7.61

-3.72

-5.11

SRVLPPLPF

7.89

-3.63

-5.02

KSRVLPPLP

8.22

-4.56

-5.95

P16892

EGEPIPPSF

8.60

-2.44

-3.83

HDPNDEPEG

10.09

-1.74

-3.13

YHDPNDEPE

11.27

0.48

-0.91

P40210

VDPTEPQTN

10.80

-0.21

-1.60

EVDPTEPQT

11.44

-0.41

-1.80

P21268

KPISPPPSL

8.27

-2.28

-3.67

LSKPISPPP

8.79

-1.73

-3.12

LNLSKPISP

10.69

-1.41

-2.80

P53950

APLLPLPSL

9.21

-3.59

-4.98

TPPAPLLPL

9.99

-2.95

-4.34

PNGAPLRRY

10.70

-2.13

-3.52

Q12753

FSIPQSPPL

7.29

-2.56

-3.95

IKPKGRPST

7.96

-3.88

-5.27

NHRYPPMAP

8.95

-5.61

-7.00

P14681

HDPSDEPEY

8.85

-0.91

-2.30

SDEPEYPPL

9.61

-0.98

-2.37

DEPEYPPLN

10.14

-1.11

-2.50

 


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