ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-23.PDB
Scoring matrix: FUS1_1OV32-23_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 16.65
Foldx random average score for Saccharomyces cerevisiae: 13.813

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1400324
Proteins after disorder filtering: 4581
 Total fragments: 56112
Proteins after pattern filtering: 1803
 Total fragments: 6184
Proteins after MINT filtering: 18
 Total fragments: 74


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

16.65

-1.35

0.00

Best peptides

RPLRYRR

0.00

-4.30

-2.95

         
Interactors      
P11710

LPLTPNS

11.20

-4.26

-2.91

PLPLTPN

13.47

-2.03

-0.68

KPLPLTP

13.54

-5.94

-4.59

Q12280

PPLRPQS

8.14

-6.24

-4.89

TPPLRPQ

12.27

-2.03

-0.68

P36119

RPTVQPS

12.01

-4.33

-2.98

P24583

LPPQPRK

10.82

-3.73

-2.38

NAPLPPQ

12.40

-2.90

-1.55

P39732

HPSIAPP

12.65

-2.86

-1.51

RHPSIAP

13.09

-3.46

-2.11

RSPSVSP

13.27

-3.06

-1.71

P21268

KPISPPP

10.77

-3.56

-2.21

SKPISPP

13.22

-2.95

-1.60

P40091

NPSHPHH

13.57

-2.97

-1.62

P40450

PKLFPRL

7.73

-5.80

-4.45

SPKLFPR

8.97

-3.88

-2.53

LPQLPPP

9.83

-3.51

-2.16

P32917

LPQHPHR

9.31

-4.20

-2.85

SPLLPPF

9.70

-3.06

-1.71

PPKVAPF

11.61

-4.13

-2.78

P25376

RPSSQPH

12.68

-2.50

-1.15

P40020

LPPLPFP

10.34

-2.33

-0.98

LPPYLSP

11.15

-3.98

-2.63

PPLTPEK

11.38

-4.74

-3.39

P41832

PPMMPAS

11.56

-6.20

-4.85

PPPVPAK

12.57

-4.14

-2.79

PPPLPSV

12.68

-3.66

-2.31

P53947

NPIQDPF

13.17

-2.95

-1.60

FNPIQDP

13.50

-3.68

-2.33

ASPFNPI

13.77

-2.10

-0.75

P34250

KPAYVPP

10.95

-4.20

-2.85

YPKEPPA

11.78

-3.07

-1.72

LYPKEPP

12.36

-2.34

-0.99

P14681

EPEYPPL

12.66

-1.88

-0.53

Q12753

SPRMPKT

10.09

-5.97

-4.62

NSPRMPK

10.38

-3.13

-1.78

PKGRPST

11.34

-3.74

-2.39

P31374

QPRLPST

9.92

-5.26

-3.91

SPERPSF

10.90

-0.18

1.17

EQPRLPS

11.50

-1.45

-0.10

P53950

APLLPLP

9.79

-4.51

-3.16

PAPLLPL

12.99

-1.09

0.26

NPSIPSA

13.23

-2.50

-1.15

 


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