ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-20.PDB
Scoring matrix: FUS1_1OV32-20_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.04
Foldx random average score for Saccharomyces cerevisiae: 15.882

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1417096
Proteins after disorder filtering: 4580
 Total fragments: 83360
Proteins after pattern filtering: 2027
 Total fragments: 7746
Proteins after MINT filtering: 21
 Total fragments: 103


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.04

-0.72

0.00

Best peptides

RMHKYGWWR

0.00

-3.04

-2.32

         
Interactors      
P11710

LPLTPNSKY

11.95

-4.54

-3.82

PLTPNSKYN

13.22

-1.26

-0.54

P36119

TRPTVQPSN

13.06

-1.19

-0.47

P53046

PPTPKSAGH

12.11

-1.74

-1.02

TPPTPKSAG

14.43

-1.60

-0.88

Q12280

SPSKPGNNN

11.23

-3.32

-2.60

PLRPQSSSK

12.24

-1.34

-0.62

APASPEEPK

12.79

-1.31

-0.59

P40073

GYPQQQPSH

13.03

-3.32

-2.60

P39732

RSPSVSPVR

13.27

-2.28

-1.56

RHPSIAPPS

14.65

-1.31

-0.59

SSPSPSPTS

15.87

-0.17

0.55

P24583

LPPQPRKHD

11.63

-6.54

-5.82

APLPPQPRK

11.94

-4.51

-3.79

RANAPLPPQ

13.36

-3.87

-3.15

P40091

SQNPSHPHH

12.50

-3.34

-2.62

PSHPHHNSR

13.46

-2.99

-2.27

TWDPSSPSS

14.36

-0.72

-0.00

P40450

SSPKLFPRL

11.91

-2.62

-1.90

PPLPNGLLS

12.41

-2.41

-1.69

SSSPKLFPR

13.00

-2.82

-2.10

P32917

RFPPYSPLL

6.79

-4.60

-3.88

IPPKVAPFG

11.10

-3.28

-2.56

DYLPQHPHR

11.52

-3.56

-2.84

P25376

DRPSSQPHL

14.62

-2.69

-1.97

NDRPSSQPH

14.98

-1.16

-0.44

PSSQPHLGY

15.45

-1.45

-0.73

P40020

PPLTPEKNL

12.00

-2.75

-2.03

YLTPESPLN

12.53

-2.44

-1.72

LYLTPESPL

12.67

-2.27

-1.55

P41832

PPPPPMALF

11.79

-4.74

-4.02

GVIPPAPPM

14.26

-4.56

-3.84

PPPPPVPAK

14.46

-3.45

-2.73

P16892

YHDPNDEPE

12.17

-1.49

-0.77

NDEPEGEPI

13.47

-1.53

-0.81

P53947

PFNPIQDPF

13.47

-1.78

-1.06

Q12114

KSEPVGTPN

15.23

0.13

0.85

P31374

NISPERPSF

10.30

-2.36

-1.64

KPPPPLDFE

10.72

-3.38

-2.66

VFPNLDPTH

11.00

-0.68

0.04

Q12753

MIKPKGRPS

10.73

-4.15

-3.43

IKPKGRPST

10.89

-2.20

-1.48

INSPRMPKT

12.56

-3.56

-2.84

P34250

PKEPPARKS

13.55

-2.56

-1.84

ALYPKEPPA

14.87

-1.99

-1.27

P14681

YHDPSDEPE

13.48

-0.67

0.05

PEYPPLNLD

15.64

-2.17

-1.45

HDPSDEPEY

15.78

0.71

1.43

P53950

SNPNGAPLR

11.74

-2.84

-2.12

SNTPPAPLL

11.87

-4.39

-3.67

DSNPNGAPL

13.19

-1.61

-0.89

 


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