ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-2.PDB
Scoring matrix: FUS1_1OV32-2_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 22.4
Foldx random average score for Saccharomyces cerevisiae: 20.792

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1375731
Proteins after disorder filtering: 4442
 Total fragments: 77166
Proteins after pattern filtering: 2131
 Total fragments: 10680
Proteins after MINT filtering: 21
 Total fragments: 141


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

22.40

10.27

0.00

Best peptides

RFKRPGRRRR

0.00

-7.46

-17.73

         
Interactors      
P11710

PLPLTPNSKY

19.83

-2.20

-12.47

PLTPNSKYNG

20.46

0.73

-9.54

P36119

SSTTRPTVQP

20.28

-1.75

-12.02

TTRPTVQPSN

20.52

0.42

-9.85

TRPTVQPSNQ

20.77

-1.06

-11.33

P53046

QLSTPPTPKS

17.30

-2.47

-12.74

NQLSTPPTPK

20.50

1.53

-8.74

Q12280

TAPASPEEPK

17.97

-1.64

-11.91

TNVTPPLRPQ

17.98

-2.03

-12.30

YSGSPSKPGN

18.98

2.48

-7.79

P40073

QFDGYPQQQP

17.81

-2.71

-12.98

P39732

SRSPSVSPVR

16.40

4.23

-6.04

RHPSIAPPSK

18.11

-0.09

-10.36

STRHPSIAPP

18.80

-1.54

-11.81

P24583

NAPLPPQPRK

16.33

-3.63

-13.90

PLPPQPRKHD

16.69

-3.21

-13.48

ANAPLPPQPR

19.98

0.59

-9.68

P21268

PISPPPSLKK

18.12

-2.67

-12.94

LNLSKPISPP

20.79

-1.12

-11.39

P40091

QNPSHPHHNS

15.56

-0.59

-10.86

GMSSPASSPV

18.29

-1.39

-11.66

NPSHPHHNSR

18.37

0.91

-9.36

P40450

VSSSPKLFPR

17.34

-0.38

-10.65

SPKLFPRLSS

18.28

-2.99

-13.26

QLPPPPPPPP

18.36

-2.20

-12.47

P32917

YLPQHPHRTS

15.72

-1.01

-11.28

RFPPYSPLLP

16.34

-1.66

-11.93

QSRFPPYSPL

17.13

-1.30

-11.57

P25376

SNDRPSSQPH

15.61

-0.76

-11.03

RPSSQPHLGY

19.13

0.03

-10.24

GSNDRPSSQP

20.13

0.06

-10.21

P40020

RNCVNPHSIP

15.42

-2.46

-12.73

VLPPLPFPLY

15.79

-3.83

-14.10

YLTPESPLNR

16.34

0.20

-10.07

P41832

GVIPPAPPMM

19.07

-2.30

-12.57

VIPPAPPMMP

19.31

-2.93

-13.20

VLSSQPPPPP

19.87

-1.02

-11.29

P16892

NDEPEGEPIP

18.58

-1.75

-12.02

TYHDPNDEPE

19.38

-2.92

-13.19

QTYHDPNDEP

20.75

0.24

-10.03

Q03466

SVPMAPDTFN

18.66

-2.01

-12.28

Q12114

SLKSEPVGTP

19.01

-2.80

-13.07

KSEPVGTPNI

20.11

-0.98

-11.25

GHETAPVSPV

20.37

-1.73

-12.00

P31374

SNKKPGTPVF

14.23

-2.60

-12.87

NNISPERPSF

15.46

1.54

-8.73

SPERPSFRQP

17.01

0.48

-9.79

Q12753

MIKPKGRPST

12.00

-4.89

-15.16

QSINSPRMPK

13.23

-2.03

-12.30

NHRYPPMAPT

16.80

-2.28

-12.55

P34250

YHSKKPSNPP

17.31

-1.97

-12.24

SALYPKEPPA

17.72

-0.83

-11.10

LYPKEPPARK

19.20

-1.37

-11.64

P53950

SNPNGAPLRR

16.26

-3.09

-13.36

DSNPNGAPLR

16.63

-1.90

-12.17

TKTAPSTAPL

18.49

-0.69

-10.96

 


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