ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-17.PDB
Scoring matrix: FUS1_1OV32-17_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 14.9
Foldx random average score for Saccharomyces cerevisiae: 17.832

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1475799
Proteins after disorder filtering: 4573
 Total fragments: 70960
Proteins after pattern filtering: 1923
 Total fragments: 6362
Proteins after MINT filtering: 20
 Total fragments: 86


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

14.90

5.55

0.00

Best peptides

RKVFPGWAH

0.00

-1.48

-7.04

         
Interactors      
P11710

LPLTPNSKY

14.89

0.28

-5.27

Q12280

VTPPLRPQS

16.30

2.95

-2.60

PPLRPQSSS

16.40

0.43

-5.13

PLRPQSSSK

16.55

2.50

-3.05

P36119

TRPTVQPSN

17.82

1.14

-4.42

P40073

GYPQQQPSH

14.45

3.00

-2.55

P24583

LPPQPRKHD

14.52

-2.22

-7.78

APLPPQPRK

15.81

0.16

-5.39

RANAPLPPQ

17.79

-1.32

-6.88

P39732

PSPSPTSSA

15.63

2.32

-3.23

RSPSVSPVR

16.39

2.02

-3.53

P40091

PSHPHHNSR

14.63

3.59

-1.96

SQNPSHPHH

14.87

1.06

-4.49

NPSHPHHNS

17.51

-1.77

-7.32

P40450

PKLFPRLSS

9.81

-0.19

-5.75

PPPLPDLFK

13.82

-3.49

-9.04

PPLPESLSM

14.32

3.08

-2.47

P32917

RFPPYSPLL

12.53

-2.03

-7.58

LPQHPHRTS

14.35

-1.58

-7.13

PQHPHRTSS

16.53

4.04

-1.51

P25376

PSSQPHLGY

14.50

2.51

-3.04

P40020

LPPLPFPLY

12.81

-4.08

-9.63

LPPYLSPQN

14.10

-0.85

-6.40

RPPPLTPEK

14.67

1.67

-3.88

P41832

PPPPPMALF

15.39

-1.94

-7.49

PPPPPVPAK

16.26

-0.48

-6.04

PPPPMALFG

16.80

0.22

-5.34

Q12114

KSEPVGTPN

17.65

2.81

-2.74

Q03466

VPMAPDTFN

17.39

0.18

-5.38

P53046

LSTPPTPKS

14.78

0.99

-4.56

PPTPKSAGH

15.93

1.74

-3.81

TPPTPKSAG

16.95

2.50

-3.05

P31374

VFPNLDPTH

13.71

4.55

-1.00

SPERPSFRQ

13.73

0.82

-4.73

NISPERPSF

13.83

0.99

-4.56

P53947

FNPIQDPFT

14.55

0.75

-4.80

Q12753

IKPKGRPST

13.47

2.36

-3.19

PKGRPSTTC

15.00

3.59

-1.96

PQSPPLSSM

15.35

0.51

-5.04

P34250

PKEPPARKS

16.34

1.28

-4.27

SSNPDLPTA

17.20

3.74

-1.81

P53950

APLLPLPSL

13.31

-0.14

-5.69

NPSIPSAST

15.06

1.24

-4.31

SNTPPAPLL

15.31

-0.98

-6.54

 


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