ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-11.PDB
Scoring matrix: FUS1_1OV32-11_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 11.87
Foldx random average score for Saccharomyces cerevisiae: 9.738

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1474674
Proteins after disorder filtering: 4680
 Total fragments: 84895
Proteins after pattern filtering: 2209
 Total fragments: 11603
Proteins after MINT filtering: 23
 Total fragments: 172


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

11.87

-0.13

0.00

Best peptides

KRPRWPL

0.00

-0.50

-0.37

         
Interactors      
P11710

KPLPLTP

7.96

-3.29

-3.16

LPLTPNS

8.04

-1.29

-1.16

P36119

RPTVQPS

8.34

-2.20

-2.07

PTVQPSN

9.36

-2.02

-1.89

P53046

LSTPPTP

8.26

-3.45

-3.32

TPPTPKS

8.93

-1.98

-1.85

P24583

NAPLPPQ

6.43

-3.68

-3.55

APLPPQP

8.18

-3.18

-3.05

LPPQPRK

8.68

-3.12

-2.99

P53947

ASPFNPI

6.73

-0.53

-0.40

SPFNPIQ

8.00

-3.61

-3.48

FNPIQDP

8.37

-3.02

-2.89

P34250

KKPSNPP

6.39

-2.96

-2.83

KPSNPPS

6.58

-2.70

-2.57

KPAYVPP

7.20

-3.29

-3.16

Q03466

VPMAPDT

7.66

-1.31

-1.18

Q12280

PPLRPQS

7.27

-2.99

-2.86

TPPLRPQ

7.93

-4.60

-4.47

VTPPLRP

8.01

-1.76

-1.63

P39732

RHPSIAP

7.35

-5.27

-5.14

HPSIAPP

8.58

-3.30

-3.17

RSPSVSP

8.95

-3.19

-3.06

P40091

NPSHPHH

8.96

-3.01

-2.88

DPSSPSS

9.19

-0.57

-0.44

P40450

PKLFPRL

6.28

-3.26

-3.13

APAPPPL

6.34

-4.30

-4.17

VPPPPPP

6.37

-3.72

-3.59

P25376

PSSQPHL

9.50

-0.85

-0.72

P41832

APPPPPP

6.82

-3.77

-3.64

IPPAPPM

7.02

-4.21

-4.08

TPPPPPL

7.15

-2.68

-2.55

P31374

SPERPSF

5.43

-1.71

-1.58

EQPRLPS

6.01

-0.54

-0.41

KTKPPPP

6.04

-4.57

-4.44

P32917

RFPPYSP

6.98

-4.50

-4.37

FPPYSPL

7.23

-1.48

-1.35

SPLLPPF

7.67

-3.31

-3.18

P40020

LPPLPFP

6.50

-4.45

-4.32

RVLPPLP

6.67

-5.05

-4.92

LTPESPL

6.85

1.84

1.97

P16892

GEPIPPS

7.16

-3.92

-3.79

EPIPPSF

7.58

-1.98

-1.85

EGEPIPP

9.10

-2.01

-1.88

P40210

DPTEPQT

8.01

-1.23

-1.10

Q12114

PVGTPNI

9.18

-2.78

-2.65

P21268

KPISPPP

6.63

-3.68

-3.55

SKPISPP

7.89

-3.82

-3.69

LSKPISP

7.93

-3.06

-2.93

P53950

NPSIPSA

7.14

-3.55

-3.42

APLLPLP

7.37

-3.67

-3.54

TPPAPLL

7.86

-2.86

-2.73

Q12753

PKGRPST

5.50

-3.34

-3.21

SPRMPKT

6.77

-3.41

-3.28

NSPRMPK

7.86

-0.82

-0.69

P14681

EPEYPPL

6.38

-3.37

-3.24

DEPEYPP

8.90

-0.87

-0.74

PEYPPLN

9.24

-2.75

-2.62

 


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