ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1OV32-1.PDB
Scoring matrix: FUS1_1OV32-1_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 26.1
Foldx random average score for Saccharomyces cerevisiae: 23.987

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1801812
Proteins after disorder filtering: 4661
 Total fragments: 131741
Proteins after pattern filtering: 2268
 Total fragments: 18331
Proteins after MINT filtering: 24
 Total fragments: 282


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

26.10

-2.86

0.00

Best peptides

FKWTRKPRRR

0.00

-1.43

1.43

         
Interactors      
P11710

SKPLPLTPNS

17.82

-3.62

-0.76

KPLPLTPNSK

22.56

-5.51

-2.65

LPLTPNSKYN

22.72

-4.22

-1.36

P36119

TRPTVQPSNQ

11.82

-3.72

-0.86

SSTTRPTVQP

14.49

-3.87

-1.01

STTRPTVQPS

21.72

-5.16

-2.30

P40073

FDGYPQQQPS

20.87

-1.99

0.87

DGYPQQQPSH

23.25

-2.89

-0.03

P24583

ANAPLPPQPR

17.31

-5.06

-2.20

NAPLPPQPRK

17.43

-6.49

-3.63

RANAPLPPQP

18.00

-8.78

-5.92

P53947

FNPIQDPFTD

17.30

-3.30

-0.44

ASPFNPIQDP

20.94

-6.61

-3.75

P34250

KKPSNPPSSG

12.80

-5.84

-2.98

YHSKKPSNPP

16.97

-4.96

-2.10

NSALYPKEPP

17.69

-5.72

-2.86

P53046

NQLSTPPTPK

19.08

-2.87

-0.01

TPPTPKSAGH

19.15

-4.40

-1.54

LSTPPTPKSA

19.26

-4.15

-1.29

Q12280

TNVTPPLRPQ

14.06

-4.90

-2.04

TAYSGSPSKP

15.47

-6.72

-3.86

YSGSPSKPGN

17.77

-3.49

-0.63

P39732

RHPSIAPPSK

11.18

-4.43

-1.57

RSPSVSPVRT

13.16

-4.48

-1.62

SSPSPSPTSS

16.67

-2.62

0.24

P40091

FGMSSPASSP

18.43

-2.68

0.18

QNPSHPHHNS

18.78

-3.09

-0.23

SSPASSPVTW

19.11

-5.70

-2.84

P40450

VSSSPKLFPR

12.52

-5.30

-2.44

SSPKLFPRLS

13.59

-7.86

-5.00

VSCIAAPAPP

15.54

-4.51

-1.65

P25376

DRPSSQPHLG

13.35

-5.22

-2.36

GSNDRPSSQP

14.98

-5.44

-2.58

SNDRPSSQPH

17.90

-1.99

0.87

P41832

TGDSPAPPPP

15.02

-3.78

-0.92

KGETPPPPPL

15.49

-4.39

-1.53

LSSQPPPPPP

16.01

-6.63

-3.77

Q03466

YSGSSVPMAP

13.90

-5.86

-3.00

SSVPMAPDTF

18.03

-5.74

-2.88

SGSSVPMAPD

18.89

-4.16

-1.30

P31374

RKTKPPPPLD

11.51

-6.23

-3.37

FRKTKPPPPL

11.70

-4.79

-1.93

NNISPERPSF

14.56

-2.45

0.41

P32917

VSTDYLPQHP

16.08

-6.24

-3.38

YSPLLPPFGL

16.54

-5.56

-2.70

DNIPPKVAPF

17.69

-4.21

-1.35

P40020

KKSRVLPPLP

10.80

-7.58

-4.72

PAPTSAPSIP

16.09

-6.27

-3.41

KSRVLPPLPF

16.25

-6.21

-3.35

P16892

HDPNDEPEGE

21.90

0.91

3.77

YHDPNDEPEG

22.30

-3.06

-0.20

NDEPEGEPIP

22.43

-1.80

1.06

P40210

VDPTEPQTND

20.73

-0.59

2.27

HDEVDPTEPQ

20.91

-3.44

-0.58

PHDEVDPTEP

21.06

-3.68

-0.82

Q12114

GHETAPVSPV

14.39

-3.88

-1.02

LKSEPVGTPN

18.83

-2.88

-0.02

SLKSEPVGTP

20.77

-4.44

-1.58

P21268

SKPISPPPSL

13.34

-4.07

-1.21

LNLSKPISPP

14.44

-6.42

-3.56

KPISPPPSLK

16.03

-6.53

-3.67

P53950

SNPNGAPLRR

13.59

-5.99

-3.13

SNTPPAPLLP

16.16

-5.65

-2.79

NPNGAPLRRY

16.56

-6.34

-3.48

Q12753

IKPKGRPSTT

12.71

-4.66

-1.80

INSPRMPKTG

15.34

-4.01

-1.15

VNHRYPPMAP

16.20

-6.47

-3.61

P14681

HDPSDEPEYP

17.15

0.13

2.99

SDEPEYPPLN

18.13

-4.17

-1.31

YHDPSDEPEY

20.17

-2.44

0.42

 


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