ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-5.PDB
Scoring matrix: FUS1_1FYN-5_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.98
Foldx random average score for Saccharomyces cerevisiae: 19.289

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1382945
Proteins after disorder filtering: 4425
 Total fragments: 79869
Proteins after pattern filtering: 2238
 Total fragments: 16706
Proteins after MINT filtering: 24
 Total fragments: 234


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.98

3.49

0.00

Best peptides

IMFWPKRHHR

0.00

-2.05

-5.54

         
Interactors      
P11710

PLPLTPNSKY

14.69

-1.44

-4.93

SKPLPLTPNS

16.75

2.63

-0.86

P36119

TRPTVQPSNQ

13.33

-0.60

-4.09

SSTTRPTVQP

16.32

-1.88

-5.37

RPTVQPSNQS

19.19

-5.36

-8.85

P40073

GYPQQQPSHT

16.50

-4.06

-7.55

P24583

NAPLPPQPRK

12.89

-4.83

-8.32

ERANAPLPPQ

12.96

-5.88

-9.37

PLPPQPRKHD

14.43

-6.76

-10.25

P53947

ASPFNPIQDP

15.24

-4.84

-8.33

P34250

YHSKKPSNPP

13.54

-4.51

-8.00

ALYPKEPPAR

14.32

-1.11

-4.60

NSALYPKEPP

14.75

-7.03

-10.52

P53046

QLSTPPTPKS

14.45

-1.41

-4.90

NQLSTPPTPK

16.40

-1.33

-4.82

TPPTPKSAGH

18.15

-3.45

-6.94

Q12280

TNVTPPLRPQ

14.75

-3.97

-7.46

TAYSGSPSKP

16.18

-3.72

-7.21

TAPASPEEPK

16.39

-2.19

-5.68

P39732

RHPSIAPPSK

12.89

-2.66

-6.15

STRHPSIAPP

15.90

-3.26

-6.75

NSSRSPSVSP

16.36

-4.27

-7.76

P40091

NPSHPHHNSR

15.22

-4.64

-8.13

PVTWDPSSPS

17.27

-4.33

-7.82

SQNPSHPHHN

17.54

-3.83

-7.32

P40450

KLPQLPPPPP

10.62

-5.95

-9.44

VSSSPKLFPR

11.17

-1.39

-4.88

QLPPPPPPPP

13.41

-5.45

-8.94

P25376

DRPSSQPHLG

16.27

-1.17

-4.66

GSNDRPSSQP

18.14

-2.91

-6.40

P41832

LSSQPPPPPP

13.48

-6.82

-10.31

VLSSQPPPPP

13.52

-5.42

-8.91

DSPAPPPPPP

14.83

-4.50

-7.99

Q03466

SVPMAPDTFN

17.37

-3.46

-6.95

SSVPMAPDTF

18.52

-0.99

-4.48

SGSSVPMAPD

18.67

-2.99

-6.48

P31374

ALSNKKPGTP

13.42

-3.86

-7.35

PLDFEQPRLP

14.05

-5.48

-8.97

RKTKPPPPLD

14.60

-4.80

-8.29

P32917

FPPYSPLLPP

14.04

-6.36

-9.85

YLPQHPHRTS

14.45

0.38

-3.11

LPQHPHRTSS

14.92

-6.41

-9.90

P40020

SRVLPPLPFP

11.31

-3.45

-6.94

KSRVLPPLPF

12.29

-4.31

-7.80

ISLPPYLSPQ

13.18

-2.23

-5.72

P16892

QTYHDPNDEP

18.00

-4.78

-8.27

EPEGEPIPPS

18.11

-4.12

-7.61

P40210

PHDEVDPTEP

18.36

-2.38

-5.87

HDEVDPTEPQ

18.72

1.66

-1.83

Q12114

SLKSEPVGTP

16.10

-3.07

-6.56

GHETAPVSPV

17.13

-3.13

-6.62

SGHETAPVSP

18.95

-2.12

-5.61

P21268

PLNLSKPISP

11.33

-5.49

-8.98

KPISPPPSLK

15.32

-4.98

-8.47

LNLSKPISPP

16.10

-4.38

-7.87

P53950

NPNGAPLRRY

15.64

-5.30

-8.79

VAPNPSIPSA

16.39

-1.02

-4.51

APSTAPLGST

16.61

-5.76

-9.25

Q12753

NHRYPPMAPT

9.77

-6.47

-9.96

LMMIKPKGRP

11.07

-8.09

-11.58

SPRMPKTGSR

12.08

-5.48

-8.97

P14681

EPEYPPLNLD

17.62

-5.28

-8.77

 


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