ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-4.PDB
Scoring matrix: FUS1_1FYN-4_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.76
Foldx random average score for Saccharomyces cerevisiae: 16.302

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1297838
Proteins after disorder filtering: 4180
 Total fragments: 50504
Proteins after pattern filtering: 2112
 Total fragments: 11136
Proteins after MINT filtering: 21
 Total fragments: 140


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.76

3.85

0.00

Best peptides

WFWRRYWRLR

0.00

-2.08

-5.93

         
Interactors      
P11710

PLPLTPNSKY

13.57

-2.47

-6.32

SKPLPLTPNS

16.14

0.59

-3.26

Q12280

PLRPQSSSKI

14.35

-2.12

-5.97

TNVTPPLRPQ

14.40

-1.14

-4.99

NINTAPASPE

15.07

-0.97

-4.82

P36119

TRPTVQPSNQ

14.28

-2.52

-6.37

SSTTRPTVQP

16.25

-0.10

-3.95

P40073

QFDGYPQQQP

12.62

-2.34

-6.19

DGYPQQQPSH

15.63

-0.20

-4.05

P24583

ANAPLPPQPR

12.64

-2.40

-6.25

NAPLPPQPRK

13.61

-1.67

-5.52

ERANAPLPPQ

15.57

-0.49

-4.34

P39732

RHPSIAPPSK

13.97

-2.08

-5.93

NSTRHPSIAP

14.14

0.11

-3.74

SRSPSVSPVR

14.74

0.73

-3.12

P21268

PISPPPSLKK

12.08

-6.50

-10.35

SKPISPPPSL

12.64

-2.21

-6.06

NLSKPISPPP

15.29

-0.63

-4.48

P40091

PVTWDPSSPS

13.48

-3.31

-7.16

GMSSPASSPV

14.25

-1.55

-5.40

QNPSHPHHNS

15.45

-2.57

-6.42

P40450

KLPQLPPPPP

10.44

-4.97

-8.82

AVPPPPPPPP

11.64

-3.44

-7.29

SSPKLFPRLS

11.80

-6.86

-10.71

P32917

SRFPPYSPLL

10.33

-5.16

-9.01

RFPPYSPLLP

10.37

-4.35

-8.20

PQSRFPPYSP

12.89

-3.50

-7.35

P25376

DRPSSQPHLG

13.55

-2.09

-5.94

GSNDRPSSQP

15.02

-1.51

-5.36

SNDRPSSQPH

16.08

-0.10

-3.95

P40020

KKSRVLPPLP

9.89

-6.77

-10.62

VLPPLPFPLY

10.29

-3.29

-7.14

KSRVLPPLPF

11.63

-2.56

-6.41

P41832

VIPPAPPMMP

12.21

-6.81

-10.66

SQPPPPPPPP

12.56

0.40

-3.45

VLSSQPPPPP

12.70

-3.91

-7.76

P53046

NQLSTPPTPK

13.17

-2.73

-6.58

QLSTPPTPKS

13.55

-1.67

-5.52

Q03466

SVPMAPDTFN

13.25

-1.17

-5.02

P14681

SDEPEYPPLN

15.79

-3.07

-6.92

P31374

RKTKPPPPLD

9.57

-6.08

-9.93

SFRKTKPPPP

10.95

-3.55

-7.40

FRKTKPPPPL

11.01

-3.39

-7.24

P53947

PFNPIQDPFT

15.17

-1.44

-5.29

FNPIQDPFTD

15.65

0.14

-3.71

Q12753

LMMIKPKGRP

9.59

-4.13

-7.98

NFSIPQSPPL

10.75

-2.15

-6.00

IKPKGRPSTT

11.19

-0.41

-4.26

P34250

YHSKKPSNPP

11.36

-2.57

-6.42

LYPKEPPARK

11.79

-2.32

-6.17

ALYPKEPPAR

13.43

-5.14

-8.99

P53950

VVAPNPSIPS

12.79

-4.52

-8.37

SNPNGAPLRR

13.49

-2.12

-5.97

NVVAPNPSIP

14.44

-5.67

-9.52

 


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