ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-23.PDB
Scoring matrix: FUS1_1FYN-23_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.73
Foldx random average score for Saccharomyces cerevisiae: 10.763

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1260548
Proteins after disorder filtering: 4557
 Total fragments: 56720
Proteins after pattern filtering: 1938
 Total fragments: 8343
Proteins after MINT filtering: 21
 Total fragments: 134


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

13.73

-1.07

0.00

Best peptides

MPMWPRW

0.00

-4.10

-3.03

         
Interactors      
P11710

KPLPLTP

7.99

-5.32

-4.25

LPLTPNS

8.01

-3.78

-2.71

Q12280

PPLRPQS

8.33

-3.54

-2.47

PLRPQSS

8.78

-2.80

-1.73

VTPPLRP

9.03

-3.35

-2.28

P36119

RPTVQPS

8.78

-3.07

-2.00

P40073

YPQQQPS

9.61

-1.72

-0.65

PQQQPSH

9.97

-1.85

-0.78

P24583

LPPQPRK

6.48

-3.86

-2.79

PPQPRKH

7.75

-3.52

-2.45

APLPPQP

8.60

-4.37

-3.30

P39732

HPSIAPP

9.87

-2.56

-1.49

PSIAPPS

10.00

-2.97

-1.90

RSPSVSP

10.57

-2.88

-1.81

P21268

LSKPISP

7.98

-3.81

-2.74

KPISPPP

8.52

-3.88

-2.81

SKPISPP

10.40

-2.63

-1.56

P53950

PLLPLPS

9.03

-3.97

-2.90

PSIPSAS

9.91

-1.96

-0.89

APLLPLP

9.92

-4.74

-3.67

P40450

PKLFPRL

4.75

-5.04

-3.97

PQLPPPP

8.39

-4.38

-3.31

PPLPDLF

8.57

-4.38

-3.31

P32917

PPKVAPF

7.99

-2.08

-1.01

LPQHPHR

8.17

-3.28

-2.21

PQHPHRT

8.70

-5.11

-4.04

P25376

RPSSQPH

9.87

-2.25

-1.18

P40020

RVLPPLP

7.03

-5.88

-4.81

MSLPVTP

7.54

-5.18

-4.11

PPLPFPL

8.58

-3.74

-2.67

P41832

PPMMPAS

7.45

-5.79

-4.72

PPLPSVL

9.33

-3.91

-2.84

QPPPPPP

9.64

-4.28

-3.21

P16892

EPIPPSF

8.04

-3.32

-2.25

Q03466

VPMAPDT

9.48

-2.73

-1.66

P53046

LSTPPTP

10.09

-3.23

-2.16

TPPTPKS

10.27

-1.22

-0.15

P14681

EPEYPPL

10.20

-1.47

-0.40

P31374

PERPSFR

7.68

-3.92

-2.85

KTKPPPP

7.88

-4.05

-2.98

QPRLPST

8.98

-3.08

-2.01

P53947

NPIQDPF

9.11

-2.78

-1.71

FNPIQDP

10.09

-4.16

-3.09

Q12753

SPRMPKT

6.72

-3.97

-2.90

IKPKGRP

7.70

-3.62

-2.55

FSIPQSP

8.43

-4.44

-3.37

P34250

YPKEPPA

9.10

-2.01

-0.94

KPAYVPP

9.22

-3.92

-2.85

PDLPTAL

9.49

-3.72

-2.65

 


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