ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-19.PDB
Scoring matrix: FUS1_1FYN-19_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.64
Foldx random average score for Saccharomyces cerevisiae: 15.694

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1689325
Proteins after disorder filtering: 4662
 Total fragments: 96627
Proteins after pattern filtering: 2087
 Total fragments: 8242
Proteins after MINT filtering: 22
 Total fragments: 106


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.64

-0.56

0.00

Best peptides

IRRNRGEWL

0.00

0.21

0.77

         
Interactors      
P11710

LPLTPNSKY

9.55

-2.87

-2.31

KPLPLTPNS

13.65

-1.01

-0.45

PLTPNSKYN

15.55

-0.84

-0.28

P36119

TRPTVQPSN

12.18

1.76

2.32

PTVQPSNQS

12.76

-2.29

-1.73

P40073

GYPQQQPSH

12.29

-2.04

-1.48

DGYPQQQPS

15.17

-0.68

-0.12

P24583

APLPPQPRK

12.07

-2.30

-1.74

LPPQPRKHD

13.95

-1.80

-1.24

PPQPRKHDK

14.54

-1.69

-1.13

P53947

PFNPIQDPF

12.64

-3.07

-2.51

P34250

PKEPPARKS

12.07

-2.78

-2.22

ESSNPDLPT

13.54

-2.65

-2.09

ALYPKEPPA

14.32

-2.73

-2.17

P53046

LSTPPTPKS

13.19

-1.95

-1.39

TPPTPKSAG

13.20

-1.04

-0.48

PPTPKSAGH

14.70

-4.03

-3.47

Q12280

PLRPQSSSK

13.02

-0.92

-0.36

PPLRPQSSS

13.33

-2.98

-2.42

VTPPLRPQS

13.47

0.65

1.21

P39732

RSPSVSPVR

15.43

0.36

0.92

P40091

PSHPHHNSR

11.68

-3.01

-2.45

TWDPSSPSS

13.07

-0.67

-0.11

NPSHPHHNS

13.65

-2.88

-2.32

P40450

PPLPNGLLS

10.33

-2.75

-2.19

APPLPNGLL

10.55

-3.39

-2.83

PPPLPQSLL

11.67

-5.61

-5.05

P25376

PSSQPHLGY

11.64

-3.25

-2.69

DRPSSQPHL

13.01

-1.89

-1.33

P41832

PPPPMALFG

11.97

-3.16

-2.60

PPPPPMALF

12.30

-4.21

-3.65

PPPLPSVLS

13.31

-3.57

-3.01

Q03466

VPMAPDTFN

15.11

-1.46

-0.90

PMAPDTFNV

15.14

-2.56

-2.00

P31374

VFPNLDPTH

11.39

-0.47

0.09

PGTPVFPNL

11.76

-1.67

-1.11

NISPERPSF

12.34

-0.78

-0.22

P32917

DYLPQHPHR

11.65

-2.41

-1.85

RFPPYSPLL

11.82

-2.26

-1.70

SRFPPYSPL

13.17

-3.55

-2.99

P40020

PPLTPEKNL

9.04

-6.19

-5.63

LYLTPESPL

11.24

-1.82

-1.26

LPPLPFPLY

11.56

-5.50

-4.94

Q12114

KSEPVGTPN

15.03

-0.60

-0.04

P40210

DPTEPQTND

14.17

-0.36

0.20

P53950

APLLPLPSL

8.66

-3.10

-2.54

DSNPNGAPL

11.06

-2.55

-1.99

VAPNPSIPS

14.22

-0.88

-0.32

Q12753

PRMPKTGSR

10.27

-2.36

-1.80

MIKPKGRPS

11.23

-4.21

-3.65

INSPRMPKT

11.98

-3.07

-2.51

P14681

PEYPPLNLD

15.47

-0.85

-0.29

 


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