ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-16.PDB
Scoring matrix: FUS1_1FYN-16_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 16.46
Foldx random average score for Saccharomyces cerevisiae: 15.799

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1466063
Proteins after disorder filtering: 4617
 Total fragments: 84872
Proteins after pattern filtering: 2164
 Total fragments: 10538
Proteins after MINT filtering: 23
 Total fragments: 119


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

16.46

0.30

0.00

Best peptides

WWPFKSIHY

0.00

2.95

2.65

         
Interactors      
P11710

LPLTPNSKY

10.49

-3.81

-4.11

PLPLTPNSK

14.65

-1.68

-1.98

SKPLPLTPN

15.64

-0.88

-1.18

P36119

RPTVQPSNQ

13.15

-1.08

-1.38

STTRPTVQP

15.64

-2.41

-2.71

P40073

FDGYPQQQP

11.14

-1.48

-1.78

GYPQQQPSH

14.54

-1.62

-1.92

P24583

LPPQPRKHD

13.06

-3.63

-3.93

NAPLPPQPR

13.27

-2.77

-3.07

ERANAPLPP

14.70

-1.88

-2.18

P53947

ASPFNPIQD

14.31

0.38

0.08

FNPIQDPFT

15.04

0.34

0.04

P34250

HSKKPSNPP

11.76

-2.20

-2.50

LYPKEPPAR

12.17

-3.15

-3.45

YHSKKPSNP

12.40

-0.89

-1.19

P53046

TPPTPKSAG

13.60

-0.50

-0.80

Q12280

SPSKPGNNN

11.98

-2.26

-2.56

YSGSPSKPG

13.04

0.05

-0.25

TPPLRPQSS

13.25

-2.43

-2.73

P39732

HPSIAPPSK

11.40

-4.17

-4.47

RSPSVSPVR

11.72

-1.00

-1.30

SSRSPSVSP

13.24

-0.55

-0.85

P40091

DPSSPSSVG

12.38

0.40

0.10

SPASSPVTW

13.62

-1.51

-1.81

NPSHPHHNS

14.58

-2.28

-2.58

P40450

PPPLPDLFK

11.05

-3.99

-4.29

LPQLPPPPP

12.49

-5.53

-5.83

PKLFPRLSS

12.96

-2.30

-2.60

P25376

RPSSQPHLG

11.36

-1.30

-1.60

PSSQPHLGY

12.99

-0.08

-0.38

SNDRPSSQP

13.69

0.55

0.25

P41832

PPPLPSVLS

11.68

-2.86

-3.16

IPPAPPMMP

12.68

-2.11

-2.41

PPPPMALFG

14.39

-0.21

-0.51

Q03466

SVPMAPDTF

14.99

-2.05

-2.35

P31374

FPNLDPTHS

11.25

-3.61

-3.91

SPERPSFRQ

11.63

-1.79

-2.09

FRKTKPPPP

12.38

-5.06

-5.36

P32917

FPPYSPLLP

9.31

-1.13

-1.43

IPPKVAPFG

10.24

-1.30

-1.60

YSPLLPPFG

11.04

-2.18

-2.48

P40020

LPPLPFPLY

8.60

-4.03

-4.33

LPPYLSPQN

10.14

-2.22

-2.52

SRVLPPLPF

12.11

-2.73

-3.03

P16892

HDPNDEPEG

14.15

1.18

0.88

Q12114

GHETAPVSP

13.68

-0.28

-0.58

LKSEPVGTP

14.88

-1.76

-2.06

P21268

LNLSKPISP

12.15

-1.34

-1.64

P53950

VAPNPSIPS

13.57

0.26

-0.04

NPNGAPLRR

14.27

-1.83

-2.13

PNGAPLRRY

14.57

-1.91

-2.21

Q12753

MMIKPKGRP

10.86

-4.79

-5.09

RNDLPDTSP

12.03

-4.31

-4.61

NHRYPPMAP

12.47

-4.30

-4.60

P14681

HDPSDEPEY

14.17

0.41

0.11

DPSDEPEYP

14.99

-1.33

-1.63

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER