ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-15.PDB
Scoring matrix: FUS1_1FYN-15_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 16.26
Foldx random average score for Saccharomyces cerevisiae: 11.265

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1511681
Proteins after disorder filtering: 4368
 Total fragments: 58598
Proteins after pattern filtering: 1875
 Total fragments: 6673
Proteins after MINT filtering: 21
 Total fragments: 79


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

16.26

0.66

0.00

Best peptides

KPRMITKDM

0.00

-3.96

-4.62

         
Interactors      
P11710

LPLTPNSKY

8.39

-4.15

-4.81

KPLPLTPNS

8.71

-0.60

-1.26

PLPLTPNSK

10.44

-3.32

-3.98

Q12280

TPPLRPQSS

10.68

-2.77

-3.43

P36119

RPTVQPSNQ

7.04

-3.25

-3.91

TRPTVQPSN

10.87

-0.74

-1.40

P40073

YPQQQPSHT

8.39

-2.09

-2.75

P24583

PPQPRKHDK

10.25

-2.07

-2.73

LPPQPRKHD

10.77

-1.99

-2.65

P39732

RSPSVSPVR

8.82

-2.07

-2.73

HPSIAPPSK

8.98

-4.06

-4.72

SPSVSPVRT

9.46

-2.93

-3.59

P21268

KPISPPPSL

10.21

-2.56

-3.22

P40091

MSSPASSPV

10.90

-1.93

-2.59

P40450

APPLPNGLL

8.52

-3.89

-4.55

PPPLPDLFK

9.08

-2.45

-3.11

PPLPESLSM

9.20

-1.91

-2.57

P32917

RFPPYSPLL

9.51

-4.18

-4.84

YSPLLPPFG

9.57

-3.14

-3.80

YLPQHPHRT

9.95

-2.84

-3.50

P25376

RPSSQPHLG

10.87

-2.51

-3.17

P40020

RPPPLTPEK

7.12

-2.85

-3.51

LPPYLSPQN

7.21

-1.19

-1.85

MSLPVTPVK

7.39

-2.23

-2.89

P41832

VIPPAPPMM

9.05

-3.20

-3.86

PPPLPSVLS

9.88

-2.82

-3.48

PPPPPLPSV

10.93

-3.53

-4.19

Q12114

SEPVGTPNI

8.93

-0.92

-1.58

P53947

PIQDPFTDN

9.82

-0.75

-1.41

FNPIQDPFT

9.94

-1.49

-2.15

SPFNPIQDP

11.05

-1.48

-2.14

P34250

YPKEPPARK

7.89

-4.28

-4.94

PAYVPPEDV

9.74

-3.17

-3.83

KPAYVPPED

9.86

-3.55

-4.21

P31374

KPGTPVFPN

8.61

-2.69

-3.35

SPERPSFRQ

9.32

-1.90

-2.56

TPVFPNLDP

9.54

-4.25

-4.91

Q12753

YPPMAPTTV

5.80

-3.27

-3.93

KPKGRPSTT

9.68

-1.91

-2.57

INSPRMPKT

9.98

-2.80

-3.46

Q03466

VPMAPDTFN

9.88

-0.40

-1.06

PMAPDTFNV

10.89

-2.06

-2.72

SVPMAPDTF

11.15

-2.41

-3.07

P53950

NPSIPSAST

9.57

-2.59

-3.25

APLLPLPSL

10.05

-4.55

-5.21

KTAPSTAPL

10.29

-1.29

-1.95

P40210

VDPTEPQTN

11.00

0.17

-0.49

PTEPQTNDS

11.11

0.27

-0.39

 


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