ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: FUS1_1FYN-14.PDB
Scoring matrix: FUS1_1FYN-14_mat
Uniprot code: P11710
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 14.38
Foldx random average score for Saccharomyces cerevisiae: 10.582

Available information for P11710 in MINT (Nov 2008):
Nš of interacting proteins: 37
 Proteins belonging to other specie: 0
Nš of interactions described: 47
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1423784
Proteins after disorder filtering: 4219
 Total fragments: 42265
Proteins after pattern filtering: 1622
 Total fragments: 4397
Proteins after MINT filtering: 16
 Total fragments: 49


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

14.38

0.45

0.00

Best peptides

FKPWIIEKR

0.00

-2.12

-2.57

         
Interactors      
P11710

LPLTPNSKY

9.09

-3.77

-4.22

P31374

ISPERPSFR

7.25

-2.10

-2.55

FPNLDPTHS

8.47

-3.38

-3.83

RKTKPPPPL

8.65

-3.41

-3.86

P36119

RPTVQPSNQ

8.38

-2.76

-3.21

P40073

YPQQQPSHT

9.40

-1.79

-2.24

P24583

NAPLPPQPR

10.15

-2.56

-3.01

P39732

RSPSVSPVR

6.97

-2.00

-2.45

HPSIAPPSK

8.45

-3.52

-3.97

SPSVSPVRT

10.49

-2.51

-2.96

P40091

MSSPASSPV

9.30

-1.95

-2.40

P40450

APPLPNGLL

9.82

-3.33

-3.78

SSPKLFPRL

9.83

-1.85

-2.30

APPPLPDLF

10.16

-1.59

-2.04

P32917

YSPLLPPFG

8.72

-3.11

-3.56

IPPKVAPFG

9.09

-1.47

-1.92

YLPQHPHRT

9.45

-2.15

-2.60

P25376

RPSSQPHLG

10.32

-0.50

-0.95

P40020

LPPLPFPLY

8.36

-3.18

-3.63

LTPESPLNR

8.80

-1.39

-1.84

LPPYLSPQN

8.96

-1.79

-2.24

P53947

FNPIQDPFT

6.74

-3.43

-3.88

ASPFNPIQD

9.83

-1.68

-2.13

P34250

LYPKEPPAR

7.56

-2.67

-3.12

YPKEPPARK

8.87

-3.38

-3.83

PAYVPPEDV

10.51

-1.20

-1.65

Q12753

YPPMAPTTV

6.34

-2.91

-3.36

IKPKGRPST

7.00

-1.13

-1.58

PKGRPSTTC

9.52

-2.44

-2.89

Q03466

SVPMAPDTF

8.92

-2.72

-3.17

P53950

NPSIPSAST

7.83

-2.77

-3.22

APLLPLPSL

10.40

-3.63

-4.08

 


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