ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1SEM-21.PDB
Scoring matrix: BUD14_1SEM-21_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 15.88
Foldx random average score for Saccharomyces cerevisiae: 15.373

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1954208
Proteins after disorder filtering: 4474
 Total fragments: 78040
Proteins after pattern filtering: 1833
 Total fragments: 5275
Proteins after MINT filtering: 14
 Total fragments: 51


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

15.88

-0.56

0.00

Best peptides

EWRPGRPTMM

0.00

-3.53

-2.97

         
Interactors      
P13186

PLTPLATNTH

10.59

-1.23

-0.67

PMSPNYGNQS

10.99

-2.24

-1.68

NIPLTPLATN

11.36

-2.66

-2.10

P27637

NESPSTPIVE

12.76

-2.69

-2.13

YQPLSPPREL

13.37

-1.87

-1.31

Q12276

QLPSRKPKRG

12.07

-1.34

-0.78

RRPSTTPSHV

12.89

-1.87

-1.31

PQRPLSGQNV

13.20

-2.09

-1.53

P38853

NKPFDTPTIQ

8.33

-6.18

-5.62

PYVPSESSQT

9.59

-2.29

-1.73

PVTPTSHQTK

10.79

-1.60

-1.04

P41818

PKTPYQGAVD

12.88

-3.23

-2.67

P40095

PRSPNRPTLS

6.83

-5.44

-4.88

STFPDSPSSS

13.11

-0.89

-0.33

P40036

ELPPLSPKST

9.38

-1.90

-1.34

KSLPTTPGIR

12.02

-3.64

-3.08

PTTPGIRSGN

13.65

-0.73

-0.17

P42073

PREPIEFDLN

9.58

-5.30

-4.74

KRPPREPIEF

10.54

-5.02

-4.46

P53858

EFEPNRPVSM

6.56

-3.58

-3.02

SMTPDSPVKS

10.64

-4.98

-4.42

DPKPSPPSSK

12.97

-2.12

-1.56

Q03016

LFSPANPKIL

9.57

-3.23

-2.67

NTKPSRPSTS

10.53

-0.75

-0.19

SRPSTSPASS

12.99

-1.29

-0.73

Q07807

FRPSNNPAAV

13.52

-2.27

-1.71

NTPVFRPSNN

15.18

-1.96

-1.40

P40187

NGNPSPPIYK

13.40

-2.73

-2.17

P39960

FFDPTLPASN

9.26

-2.45

-1.89

INNPATPNQK

10.26

-3.90

-3.34

PATPNQKMRD

13.58

-2.46

-1.90

P26570

PKSPILKTNN

9.86

-2.97

-2.41

PSTPSKPNLE

11.89

-2.66

-2.10

STPLNSPGLS

14.46

-3.39

-2.83

 


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