ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1SEM-2.PDB
Scoring matrix: BUD14_1SEM-2_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 15.03
Foldx random average score for Saccharomyces cerevisiae: 17.741

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1371007
Proteins after disorder filtering: 4629
 Total fragments: 123985
Proteins after pattern filtering: 2308
 Total fragments: 21657
Proteins after MINT filtering: 13
 Total fragments: 192


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

15.03

9.48

0.00

Best peptides

RTRHWPRKRY

0.00

4.94

-4.54

         
Interactors      
P13186

RNSSIPMSPN

8.72

-1.32

-10.80

RPPIPAALPP

10.09

-1.00

-10.48

PAALPPSDMT

10.87

-0.95

-10.43

P27637

WTNESPSTPI

7.31

1.29

-8.19

YQPLSPPREL

11.93

-0.08

-9.56

QPLSPPRELD

12.02

0.16

-9.32

Q12276

RPSTTPSHVV

11.63

0.23

-9.25

QQLPSRKPKR

11.64

2.31

-7.17

RRPSTTPSHV

11.77

5.43

-4.05

P38853

ITSNKPFDTP

9.91

-0.58

-10.06

PTDTPTPRNG

11.31

5.96

-3.52

VPTDTPTPRN

11.31

-0.12

-9.60

P40095

PVLPPPRSPN

11.30

1.02

-8.46

PPRSPNRPTL

11.33

-0.63

-10.11

PSSTFPDSPS

11.72

0.84

-8.64

P40036

FKIELPPLSP

12.32

-0.10

-9.58

PPLSPKSTVP

14.25

-1.13

-10.61

LPPLSPKSTV

15.81

2.60

-6.88

P42073

LNKRPPREPI

10.42

0.47

-9.01

RPPREPIEFD

11.76

-0.31

-9.79

NKRPPREPIE

16.29

4.04

-5.44

P53858

MTPDSPVKSD

9.87

2.69

-6.79

PKPSPPSSKL

12.95

-0.40

-9.88

TPRVKPDSQG

13.44

-1.31

-10.79

Q03016

PTASKPQTPI

8.45

0.77

-8.71

RKTNTKPSRP

10.86

0.71

-8.77

KTNTKPSRPS

11.04

1.92

-7.56

Q07807

FRPSNNPAAV

10.45

0.19

-9.29

FPFAYPNPMM

10.52

-2.64

-12.12

PSSPPNNSPF

10.96

1.72

-7.76

P40187

GNPSPPIYKK

11.48

-0.67

-10.15

NGNPSPPIYK

12.51

-0.04

-9.52

MDEPLNLPNN

13.88

3.04

-6.44

P39960

NPATPNQKMR

11.98

0.40

-9.08

INNPATPNQK

13.27

6.19

-3.29

NNPATPNQKM

13.48

0.94

-8.54

P26570

PTDSPNEWED

11.44

3.21

-6.27

STPSKPNLEV

11.75

3.66

-5.82

YSTPLNSPGL

12.62

2.59

-6.89

 


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