ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1SEM-14.PDB
Scoring matrix: BUD14_1SEM-14_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 18.7
Foldx random average score for Saccharomyces cerevisiae: 12.974

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1427414
Proteins after disorder filtering: 3877
 Total fragments: 32208
Proteins after pattern filtering: 1492
 Total fragments: 4224
Proteins after MINT filtering: 13
 Total fragments: 48


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

18.70

-0.44

0.00

Best peptides

MWPMMLWMF

0.00

-4.65

-4.21

         
Interactors      
P13186

IPLTPLATN

7.42

-3.35

-2.91

QNNIPLTPL

10.85

-5.42

-4.98

NSSIPMSPN

11.10

-2.40

-1.96

P27637

SPSTPIVEE

12.09

-2.51

-2.07

YQPLSPPRE

12.70

-3.50

-3.06

Q12276

DPPQQLPSR

10.73

-3.44

-3.00

SPQRPLSGQ

12.51

-2.96

-2.52

PPQQLPSRK

12.58

-3.17

-2.73

P38853

PTDTPTPRN

11.98

-1.89

-1.45

PFDTPTIQK

12.01

-1.46

-1.02

NKPFDTPTI

12.25

-4.46

-4.02

P40095

IPVLPPPRS

11.02

-6.47

-6.03

RIPVLPPPR

11.06

-3.34

-2.90

VLPPPRSPN

12.40

-1.35

-0.91

P40036

IELPPLSPK

12.04

-2.75

-2.31

SLPTTPGIR

12.30

-0.92

-0.48

P42073

RPPREPIEF

9.84

-1.57

-1.13

KRPPREPIE

12.19

-3.29

-2.85

PPREPIEFD

12.48

-4.36

-3.92

P53858

EPNRPVSMS

10.87

-4.84

-4.40

AYLPEFEPN

11.77

-1.38

-0.94

KPSPPSSKL

12.90

-3.79

-3.35

Q03016

NIPLLTPIN

8.46

-2.64

-2.20

DPPQQLPSR

10.73

-3.44

-3.00

IPLLTPINS

11.42

-4.38

-3.94

Q07807

NTPVFRPSN

10.07

-0.11

0.33

PFAYPNPMM

10.80

-5.09

-4.65

MMFMPPPPL

10.90

-6.15

-5.71

P40187

DEPLNLPNN

10.16

-2.89

-2.45

NPSPPIYKK

11.76

-4.09

-3.65

P39960

NPATPNQKM

12.33

-4.39

-3.95

FFDPTLPAS

12.67

-2.65

-2.21

P26570

PKSPILKTN

10.55

-2.95

-2.51

MEPKSPILK

11.10

-2.13

-1.69

EPKSPILKT

11.78

-4.21

-3.77

 


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