ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1SEM-12.PDB
Scoring matrix: BUD14_1SEM-12_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.15
Foldx random average score for Saccharomyces cerevisiae: 10.942

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1353522
Proteins after disorder filtering: 4570
 Total fragments: 80121
Proteins after pattern filtering: 2189
 Total fragments: 13097
Proteins after MINT filtering: 13
 Total fragments: 135


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

14.15

-1.69

0.00

Best peptides

RRMRRWWK

0.00

-6.28

-4.59

         
Interactors      
P13186

LPEREPPT

6.60

-5.88

-4.19

PSYVPNRV

7.22

-4.93

-3.24

IPMSPNYG

8.64

-4.23

-2.54

P27637

DYQPLSPP

8.85

-2.50

-0.81

YQPLSPPR

8.87

-3.85

-2.16

DDYQPLSP

9.51

-3.77

-2.08

Q12276

SPQRPLSG

7.33

-5.96

-4.27

PQQLPSRK

7.92

-3.50

-1.81

TRPKILPK

8.05

-4.26

-2.57

P38853

NKPFDTPT

8.99

-3.13

-1.44

SNKPFDTP

10.12

-4.01

-2.32

ASAPSPAP

10.30

-3.21

-1.52

P40095

PPPRSPNR

7.04

-6.80

-5.11

STFPDSPS

7.83

-3.67

-1.98

PVLPPPRS

8.10

-4.78

-3.09

P40036

IELPPLSP

8.77

-4.01

-2.32

PTTPGIRS

9.05

-4.57

-2.88

ELPPLSPK

9.18

-2.96

-1.27

P42073

RPPREPIE

8.15

-6.28

-4.59

KRPPREPI

8.92

-3.82

-2.13

PREPIEFD

9.59

-2.79

-1.10

P53858

PEFEPNRP

6.49

-4.72

-3.03

STPRVKPD

7.70

-5.26

-3.57

LPEFEPNR

7.88

-4.59

-2.90

Q03016

LFSPANPK

8.34

-2.83

-1.14

PQQLPSRT

8.47

-4.00

-2.31

ANPKILPK

8.69

-4.45

-2.76

Q07807

PVFRPSNN

5.24

-5.83

-4.14

VFRPSNNP

6.74

-3.55

-1.86

MFMPPPPL

6.86

-5.20

-3.51

P40187

MDEPLNLP

6.94

-3.22

-1.53

PSPPIYKK

8.18

-4.83

-3.14

PLNLPNNS

8.37

-4.85

-3.16

P39960

PTLPASNS

9.27

-3.69

-2.00

KFFDPTLP

9.65

-0.44

1.25

FFDPTLPA

10.09

-3.20

-1.51

P26570

YSTPLNSP

8.86

-3.98

-2.29

MEPKSPIL

9.71

-3.95

-2.26

STPSKPNL

9.90

-3.41

-1.72

 


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