ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1GCQ-9.PDB
Scoring matrix: BUD14_1GCQ-9_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 18.91
Foldx random average score for Saccharomyces cerevisiae: 13.487

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1330483
Proteins after disorder filtering: 4334
 Total fragments: 51185
Proteins after pattern filtering: 2059
 Total fragments: 10153
Proteins after MINT filtering: 13
 Total fragments: 99


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

18.91

-1.89

0.00

Best peptides

RRWWWRFM

0.00

-5.84

-3.95

         
Interactors      
P13186

RPPIPAAL

8.49

-5.55

-3.66

IPLTPLAT

10.13

-4.75

-2.86

QNNIPLTP

10.27

-6.25

-4.36

P27637

YQPLSPPR

11.77

-5.79

-3.90

QPLSPPRE

12.90

-4.65

-2.76

SPSTPIVE

13.11

-3.56

-1.67

Q12276

LPSRKPKR

10.76

-4.63

-2.74

PQQLPSRK

11.47

-4.64

-2.75

ASPQRPLS

11.77

-3.82

-1.93

P38853

NKPFDTPT

12.87

-2.55

-0.66

P40095

IPVLPPPR

8.52

-8.08

-6.19

RIPVLPPP

9.07

-6.62

-4.73

NNRIPVLP

9.77

-6.84

-4.95

P40036

LPPLSPKS

8.36

-4.80

-2.91

SKSLPTTP

11.00

-5.53

-3.64

LPTTPGIR

11.35

-5.02

-3.13

P42073

PPREPIEF

10.62

-6.00

-4.11

RPPREPIE

11.40

-2.69

-0.80

NKRPPREP

12.31

-4.78

-2.89

P53858

FEPNRPVS

10.87

-3.12

-1.23

EPNRPVSM

11.78

-3.95

-2.06

TPRVKPDS

12.01

-3.58

-1.69

Q03016

PQQLPSRT

10.21

-4.99

-3.10

KPQTPILP

10.33

-5.69

-3.80

RPSTSPAS

10.93

-1.85

0.04

Q07807

PNPIPVKM

8.35

-6.27

-4.38

MMFMPPPP

8.84

-8.92

-7.03

FMPPPPLS

8.92

-6.89

-5.00

P40187

PLNLPNNS

11.35

-5.33

-3.44

MDEPLNLP

11.74

-6.66

-4.77

GNPSPPIY

11.91

-4.50

-2.61

P39960

FDPTLPAS

10.40

-4.38

-2.49

KFFDPTLP

11.09

-4.90

-3.01

NPATPNQK

11.57

-5.24

-3.35

P26570

EPKSPILK

11.46

-5.37

-3.48

MEPKSPIL

11.69

-3.98

-2.09

DPSTPSKP

11.87

-4.69

-2.80

 


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