ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1GCQ-7.PDB
Scoring matrix: BUD14_1GCQ-7_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 13.72
Foldx random average score for Saccharomyces cerevisiae: 10.893

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1395629
Proteins after disorder filtering: 4441
 Total fragments: 56829
Proteins after pattern filtering: 2156
 Total fragments: 12134
Proteins after MINT filtering: 13
 Total fragments: 103


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

13.72

-0.61

0.00

Best peptides

WRPMPPWR

0.00

-6.18

-5.57

         
Interactors      
P13186

PSYVPNRV

7.97

-3.45

-2.84

IPMSPNYG

8.23

-4.55

-3.94

PEREPPTY

8.56

-4.06

-3.45

P27637

YQPLSPPR

8.23

-3.92

-3.31

QPLSPPRE

8.44

-2.95

-2.34

PLSPPREL

8.64

-4.05

-3.44

Q12276

PQQLPSRK

5.91

-5.11

-4.50

LPSRKPKR

6.79

-3.31

-2.70

PSRKPKRG

7.41

-4.30

-3.69

P38853

PTDTPTPR

8.93

-3.36

-2.75

PFDTPTIQ

9.01

-4.15

-3.54

PSPAPKDF

9.54

-2.54

-1.93

P40095

IPVLPPPR

4.85

-6.67

-6.06

PVLPPPRS

8.04

-4.14

-3.53

RIPVLPPP

9.46

-4.60

-3.99

P40036

LPTTPGIR

7.33

-4.58

-3.97

LPPLSPKS

8.20

-3.72

-3.11

ELPPLSPK

8.40

-3.38

-2.77

P42073

KRPPREPI

8.31

-2.30

-1.69

PPREPIEF

8.77

-4.32

-3.71

NKRPPREP

9.31

-4.40

-3.79

P53858

YLPEFEPN

8.88

-1.23

-0.62

PKPSPPSS

9.24

-3.33

-2.72

KPSPPSSK

9.30

-3.40

-2.79

Q03016

PQQLPSRT

6.84

-4.49

-3.88

NIPLLTPI

8.48

-3.69

-3.08

PSRTPKKG

8.63

-4.08

-3.47

Q07807

MMFMPPPP

6.56

-7.20

-6.59

PNPIPVKM

7.54

-4.90

-4.29

FMPPPPLS

7.61

-5.86

-5.25

P40187

NPSPPIYK

8.00

-4.86

-4.25

PLNLPNNS

8.62

-4.42

-3.81

GNPSPPIY

9.03

-3.85

-3.24

P39960

DPTLPASN

9.50

-4.21

-3.60

NPATPNQK

9.65

-4.85

-4.24

FDPTLPAS

9.76

-4.45

-3.84

P26570

EPKSPILK

9.18

-4.35

-3.74

TPSKPNLE

9.71

-3.21

-2.60

MEPKSPIL

9.77

-2.37

-1.76

 


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