ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1GCQ-5.PDB
Scoring matrix: BUD14_1GCQ-5_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.43
Foldx random average score for Saccharomyces cerevisiae: 21.622

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1533898
Proteins after disorder filtering: 4687
 Total fragments: 143969
Proteins after pattern filtering: 2305
 Total fragments: 22107
Proteins after MINT filtering: 13
 Total fragments: 183


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.43

1.01

0.00

Best peptides

RGYNMPRHHW

0.00

-3.46

-4.47

         
Interactors      
P13186

RNSSIPMSPN

11.63

-4.85

-5.86

RPPIPAALPP

14.14

-2.15

-3.16

YDFKAPSYVP

14.30

-3.57

-4.58

P27637

WTNESPSTPI

12.92

-1.70

-2.71

QPLSPPRELD

13.65

-2.56

-3.57

NDDYQPLSPP

15.30

-2.99

-4.00

Q12276

SGTRPKILPK

10.72

-3.61

-4.62

TSGTRPKILP

11.91

-2.73

-3.74

ASPQRPLSGQ

13.12

-3.38

-4.39

P38853

ITSNKPFDTP

13.48

-1.98

-2.99

SAPSPAPKDF

13.57

-2.02

-3.03

TSNKPFDTPT

13.67

-1.03

-2.04

P40095

IPVLPPPRSP

11.88

-5.41

-6.42

RSPNRPTLSD

11.91

-1.25

-2.26

SSPTPAPSSG

13.50

-0.11

-1.12

P40036

LPPLSPKSTV

12.33

-6.05

-7.06

LPTTPGIRSG

15.95

0.56

-0.45

PPLSPKSTVP

18.32

-3.47

-4.48

P42073

LNKRPPREPI

10.48

-4.38

-5.39

RPPREPIEFD

13.35

-2.49

-3.50

DLNKRPPREP

20.99

1.42

0.41

P53858

IDSMTPDSPV

13.52

3.40

2.39

LPEFEPNRPV

13.90

-3.26

-4.27

TPRVKPDSQG

15.53

-1.19

-2.20

Q03016

KGKHPPISSP

8.48

-4.61

-5.62

FSPANPKILP

12.57

-3.46

-4.47

LPSRTPKKGN

13.10

-2.87

-3.88

Q07807

SSVSSPSSPP

12.66

-2.11

-3.12

SPPNNSPFPF

13.68

-1.05

-2.06

SSPSSPPNNS

13.73

-1.00

-2.01

P40187

NGNPSPPIYK

12.94

-3.47

-4.48

GNPSPPIYKK

14.40

-1.76

-2.77

ENGNPSPPIY

16.06

1.02

0.01

P39960

NPATPNQKMR

15.29

-3.45

-4.46

FDPTLPASNS

16.01

-0.94

-1.95

SMLINNPATP

16.42

-0.14

-1.15

P26570

TAYSTPLNSP

12.12

-5.10

-6.11

TPLNSPGLSK

14.22

-1.88

-2.89

SDPTDSPNEW

14.28

-0.51

-1.52

 


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