ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1GCQ-29.PDB
Scoring matrix: BUD14_1GCQ-29_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.62
Foldx random average score for Saccharomyces cerevisiae: 15.988

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1555425
Proteins after disorder filtering: 4182
 Total fragments: 55114
Proteins after pattern filtering: 2059
 Total fragments: 11328
Proteins after MINT filtering: 13
 Total fragments: 120


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.62

-1.69

0.00

Best peptides

RRRMWFFNRK

0.00

-8.33

-6.64

         
Interactors      
P13186

KAPSYVPNRV

10.00

-7.91

-6.22

SSIPMSPNYG

10.83

-8.00

-6.31

PLTPLATNTH

10.94

-6.73

-5.04

P27637

DYQPLSPPRE

12.25

-7.46

-5.77

YQPLSPPREL

15.36

-6.31

-4.62

TNMSDPASKP

15.88

-4.99

-3.30

Q12276

QLPSRKPKRG

10.84

-6.26

-4.57

DPPQQLPSRK

11.93

-6.99

-5.30

PQRPLSGQNV

12.93

-5.17

-3.48

P38853

NKPFDTPTIQ

14.55

-4.44

-2.75

DVPTDTPTPR

14.93

-6.13

-4.44

APSPAPKDFS

15.46

-5.12

-3.43

P40095

RIPVLPPPRS

9.11

-9.18

-7.49

NRIPVLPPPR

11.09

-8.02

-6.33

LPPPRSPNRP

11.90

-5.23

-3.54

P40036

ELPPLSPKST

12.04

-6.78

-5.09

SLPTTPGIRS

12.05

-8.74

-7.05

FKIELPPLSP

13.56

-7.43

-5.74

P42073

PREPIEFDLN

11.70

-4.78

-3.09

KRPPREPIEF

13.59

-5.44

-3.75

NKRPPREPIE

13.63

-6.39

-4.70

P53858

YLPEFEPNRP

8.76

-6.69

-5.00

AYLPEFEPNR

11.81

-6.81

-5.12

PKPSPPSSKL

13.47

-5.60

-3.91

Q03016

NIPLLTPINS

12.44

-7.41

-5.72

DPPQQLPSRT

12.47

-6.59

-4.90

QLPSRTPKKG

13.02

-6.02

-4.33

Q07807

PMMFMPPPPL

11.39

-9.37

-7.68

NPMMFMPPPP

12.25

-8.46

-6.77

PFPFAYPNPM

12.80

-7.88

-6.19

P40187

DEPLNLPNNS

11.21

-7.51

-5.82

EPLNLPNNSA

12.80

-7.12

-5.43

NGNPSPPIYK

14.88

-5.53

-3.84

P39960

NIKFFDPTLP

12.64

-6.20

-4.51

FDPTLPASNS

13.19

-6.00

-4.31

MLINNPATPN

13.43

-6.92

-5.23

P26570

PKSPILKTNN

12.83

-4.72

-3.03

PLNSPGLSKL

14.28

-2.35

-0.66

MEPKSPILKT

14.71

-6.75

-5.06

 


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