ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1GCQ-23.PDB
Scoring matrix: BUD14_1GCQ-23_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 15.69
Foldx random average score for Saccharomyces cerevisiae: 11.658

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1394100
Proteins after disorder filtering: 4493
 Total fragments: 57311
Proteins after pattern filtering: 1991
 Total fragments: 10484
Proteins after MINT filtering: 13
 Total fragments: 94


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

15.69

-0.83

0.00

Best peptides

MPLRYRM

0.00

-5.95

-5.12

         
Interactors      
P13186

LPEREPP

7.33

-5.12

-4.29

PPIPAAL

8.38

-6.38

-5.55

RPPIPAA

9.32

-5.17

-4.34

P27637

YQPLSPP

9.19

-4.62

-3.79

PLSPPRE

9.71

-3.85

-3.02

QPLSPPR

10.09

-4.37

-3.54

Q12276

LPSRKPK

7.77

-4.93

-4.10

RPKILPK

8.04

-5.46

-4.63

SPQRPLS

9.26

-1.30

-0.47

P38853

LATPVTP

11.05

-4.88

-4.05

NKPFDTP

11.17

-4.99

-4.16

P40095

PPPRSPN

8.26

-4.19

-3.36

PVLPPPR

8.53

-5.86

-5.03

NRIPVLP

8.82

-6.60

-5.77

P40036

LPPLSPK

8.05

-5.74

-4.91

KSLPTTP

8.88

-6.19

-5.36

ELPPLSP

10.18

-4.67

-3.84

P42073

RPPREPI

5.92

-3.41

-2.58

KRPPREP

10.15

-5.10

-4.27

PREPIEF

10.97

-3.43

-2.60

P53858

EFEPNRP

8.82

-5.37

-4.54

STPRVKP

8.89

-3.71

-2.88

EPNRPVS

9.39

-4.07

-3.24

Q03016

IPLLTPI

7.00

-6.38

-5.55

LPSRTPK

7.91

-5.54

-4.71

NTKPSRP

8.26

-5.48

-4.65

Q07807

MFMPPPP

7.92

-6.24

-5.41

FMPPPPL

8.68

-5.19

-4.36

MPPPPLS

8.97

-5.63

-4.80

P40187

PSPPIYK

9.56

-4.89

-4.06

EPLNLPN

10.11

-4.94

-4.11

DEPLNLP

10.11

-4.07

-3.24

P39960

PTLPASN

9.87

-5.58

-4.75

DPTLPAS

11.20

-4.02

-3.19

P26570

MEPKSPI

9.50

-4.95

-4.12

PSKPNLE

10.71

-4.35

-3.52

EPKSPIL

10.78

-3.72

-2.89

 


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