ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1GCQ-1.PDB
Scoring matrix: BUD14_1GCQ-1_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 23.4
Foldx random average score for Saccharomyces cerevisiae: 28.864

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1892745
Proteins after disorder filtering: 4724
 Total fragments: 167882
Proteins after pattern filtering: 2306
 Total fragments: 23020
Proteins after MINT filtering: 13
 Total fragments: 197


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

23.40

-3.04

0.00

Best peptides

YPQNWYRRRY

0.00

-2.99

0.05

         
Interactors      
P13186

IPLTPLATNT

15.48

-2.65

0.39

RPPIPAALPP

15.52

-6.46

-3.42

IPAALPPSDM

16.06

-3.13

-0.09

P27637

QPLSPPRELD

14.91

-6.04

-3.00

YQPLSPPREL

20.23

-1.88

1.16

NDDYQPLSPP

20.38

-4.14

-1.10

Q12276

DPPQQLPSRK

12.40

-7.26

-4.22

SPQRPLSGQN

13.34

-4.69

-1.65

PPQQLPSRKP

14.31

-7.39

-4.35

P38853

VPTDTPTPRN

15.39

-3.19

-0.15

KPFDTPTIQK

15.96

-5.81

-2.77

TSNKPFDTPT

16.96

-6.55

-3.51

P40095

LPPPRSPNRP

13.88

-4.27

-1.23

IPVLPPPRSP

13.93

-5.76

-2.72

PPSSTFPDSP

14.26

-6.38

-3.34

P40036

LPPLSPKSTV

15.99

-2.90

0.14

PPLSPKSTVP

18.77

-5.76

-2.72

KSLPTTPGIR

19.09

-2.74

0.30

P42073

RPPREPIEFD

17.13

-4.70

-1.66

LNKRPPREPI

17.40

-4.08

-1.04

PPREPIEFDL

24.30

-2.22

0.82

P53858

TPRVKPDSQG

15.00

-4.40

-1.36

LPEFEPNRPV

15.94

-1.19

1.85

DPKPSPPSSK

16.72

-2.42

0.62

Q03016

SPANPKILPK

13.04

-4.67

-1.63

DPPQQLPSRT

13.24

-6.52

-3.48

PPQQLPSRTP

15.67

-5.42

-2.38

Q07807

FPFAYPNPMM

11.96

-5.56

-2.52

SPPNNSPFPF

12.73

-3.90

-0.86

YPTPNPIPVK

13.56

-5.08

-2.04

P40187

EPLNLPNNSA

15.85

-4.45

-1.41

ENGNPSPPIY

17.65

-0.95

2.09

SEENGNPSPP

18.89

-0.42

2.62

P39960

NPATPNQKMR

15.13

-4.84

-1.80

FDPTLPASNS

18.55

-6.31

-3.27

PATPNQKMRD

19.98

-4.48

-1.44

P26570

TPLNSPGLSK

14.16

-4.72

-1.68

VPDPSTPSKP

15.83

-3.65

-0.61

TPSKPNLEVN

16.02

-3.33

-0.29

 


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