ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKB-7.PDB
Scoring matrix: BUD14_1CKB-7_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 13.3
Foldx random average score for Saccharomyces cerevisiae: 10.218

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1435413
Proteins after disorder filtering: 4550
 Total fragments: 64930
Proteins after pattern filtering: 2213
 Total fragments: 12608
Proteins after MINT filtering: 13
 Total fragments: 112


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

13.30

-1.62

0.00

Best peptides

WRDMMPWW

0.00

-1.77

-0.15

         
Interactors      
P13186

IPMSPNYG

6.73

-4.54

-2.92

PEREPPTY

7.70

-4.68

-3.06

PSYVPNRV

7.80

-4.34

-2.72

P27637

QPLSPPRE

6.77

-3.19

-1.57

YQPLSPPR

7.69

-4.24

-2.62

PLSPPREL

9.20

-4.15

-2.53

Q12276

LPSRKPKR

6.24

-6.15

-4.53

PQQLPSRK

6.80

-6.54

-4.92

PPQQLPSR

6.87

-4.97

-3.35

P38853

PFDTPTIQ

8.16

-4.58

-2.96

PTDTPTPR

8.57

-4.40

-2.78

PSPAPKDF

8.65

-3.48

-1.86

P40095

IPVLPPPR

5.19

-8.36

-6.74

NNRIPVLP

7.78

-5.79

-4.17

PVLPPPRS

8.14

-4.14

-2.52

P40036

LPTTPGIR

6.60

-5.28

-3.66

LPPLSPKS

8.23

-4.91

-3.29

ELPPLSPK

8.58

-3.96

-2.34

P42073

PPREPIEF

6.47

-4.65

-3.03

NKRPPREP

8.97

-4.57

-2.95

PREPIEFD

9.26

-2.94

-1.32

P53858

LPEFEPNR

7.49

-4.76

-3.14

KPSPPSSK

7.80

-4.33

-2.71

TPDSPVKS

7.91

-3.43

-1.81

Q03016

PPQQLPSR

6.87

-4.97

-3.35

PQQLPSRT

7.69

-6.11

-4.49

KPQTPILP

8.04

-5.45

-3.83

Q07807

PNPIPVKM

6.15

-6.02

-4.40

FMPPPPLS

6.66

-4.34

-2.72

MMFMPPPP

6.79

-6.85

-5.23

P40187

NPSPPIYK

7.34

-5.10

-3.48

MDEPLNLP

7.56

-6.53

-4.91

GNPSPPIY

7.77

-3.31

-1.69

P39960

NPATPNQK

7.07

-3.98

-2.36

KFFDPTLP

7.78

-5.13

-3.51

DPTLPASN

8.40

-5.13

-3.51

P26570

EPKSPILK

6.67

-5.10

-3.48

TPSKPNLE

7.30

-4.67

-3.05

PTDSPNEW

7.37

-3.40

-1.78

 


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