ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKB-4.PDB
Scoring matrix: BUD14_1CKB-4_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 16.52
Foldx random average score for Saccharomyces cerevisiae: 18.918

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1186496
Proteins after disorder filtering: 4566
 Total fragments: 98855
Proteins after pattern filtering: 2304
 Total fragments: 20827
Proteins after MINT filtering: 14
 Total fragments: 179


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

16.52

7.58

0.00

Best peptides

MFPRRFRRKR

0.00

4.25

-3.33

         
Interactors      
P13186

FKAPSYVPNR

12.01

-0.11

-7.69

QQEPLPEREP

12.92

0.35

-7.23

APSYVPNRVP

13.51

-4.21

-11.79

P27637

QPLSPPRELD

12.69

-1.47

-9.05

TNMSDPASKP

13.05

-1.12

-8.70

DYQPLSPPRE

13.29

0.34

-7.24

Q12276

ASPQRPLSGQ

12.08

-1.80

-9.38

TSGTRPKILP

12.22

-0.16

-7.74

QQLPSRKPKR

13.14

-1.50

-9.08

P38853

ATPVTPTSHQ

10.96

0.45

-7.13

ASAPSPAPKD

11.73

-0.50

-8.08

VPTDTPTPRN

12.65

-1.37

-8.95

P41818

PKTPYQGAVD

18.41

0.53

-7.05

P40095

TFPDSPSSSS

10.08

-1.02

-8.60

PPPRSPNRPT

13.13

-1.00

-8.58

IPVLPPPRSP

13.64

-2.77

-10.35

P40036

FKIELPPLSP

13.65

-1.89

-9.47

ELPPLSPKST

17.37

1.60

-5.98

SLPTTPGIRS

17.44

1.04

-6.54

P42073

LNKRPPREPI

14.97

-1.53

-9.11

RPPREPIEFD

16.18

-0.86

-8.44

DLNKRPPREP

16.44

1.73

-5.85

P53858

AYLPEFEPNR

5.99

-1.24

-8.82

DFLSTPRVKP

8.97

-2.82

-10.40

MTPDSPVKSD

10.37

0.33

-7.25

Q03016

PTASKPQTPI

12.38

0.01

-7.57

TKPSRPSTSP

12.60

-2.85

-10.43

FSPANPKILP

13.53

-1.92

-9.50

Q07807

MFMPPPPLSA

6.82

-2.04

-9.62

PFPFAYPNPM

7.65

-3.53

-11.11

VFRPSNNPAA

9.51

-4.21

-11.79

P40187

GNPSPPIYKK

12.60

-1.91

-9.49

NGNPSPPIYK

14.07

-0.45

-8.03

MDEPLNLPNN

16.34

0.17

-7.41

P39960

NNPATPNQKM

12.28

1.03

-6.55

IKFFDPTLPA

14.92

4.03

-3.55

NPATPNQKMR

15.26

-0.64

-8.22

P26570

MEPKSPILKT

12.13

-1.98

-9.56

STPSKPNLEV

14.69

1.56

-6.02

PDPSTPSKPN

14.69

-0.40

-7.98

 


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