ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKB-29.PDB
Scoring matrix: BUD14_1CKB-29_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 19.91
Foldx random average score for Saccharomyces cerevisiae: 14.817

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1494898
Proteins after disorder filtering: 4119
 Total fragments: 54351
Proteins after pattern filtering: 2109
 Total fragments: 14442
Proteins after MINT filtering: 13
 Total fragments: 142


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

19.91

-0.43

0.00

Best peptides

RRKMMHPYRK

0.00

-4.39

-3.96

         
Interactors      
P13186

KAPSYVPNRV

11.39

-7.56

-7.13

SSIPMSPNYG

11.42

-6.68

-6.25

PLTPLATNTH

11.80

-7.02

-6.59

P27637

QPLSPPRELD

10.98

-6.66

-6.23

DYQPLSPPRE

11.10

-6.14

-5.71

YQPLSPPREL

12.91

-4.97

-4.54

Q12276

QLPSRKPKRG

7.11

-6.49

-6.06

PPQQLPSRKP

8.99

-6.26

-5.83

RRPSTTPSHV

9.67

-4.56

-4.13

P38853

KPFDTPTIQK

11.17

-6.21

-5.78

GVMDVPTDTP

12.70

-5.96

-5.53

APSPAPKDFS

13.19

-5.15

-4.72

P40095

NRIPVLPPPR

8.92

-8.39

-7.96

LPPPRSPNRP

10.04

-7.39

-6.96

PRSPNRPTLS

10.07

-5.20

-4.77

P40036

ELPPLSPKST

8.63

-6.57

-6.14

SLPTTPGIRS

10.21

-8.98

-8.55

FKIELPPLSP

12.31

-7.36

-6.93

P42073

DLNKRPPREP

10.21

-8.05

-7.62

KRPPREPIEF

10.45

-5.60

-5.17

RPPREPIEFD

11.37

-7.10

-6.67

P53858

YLPEFEPNRP

8.97

-6.89

-6.46

DFLSTPRVKP

10.65

-7.73

-7.30

FLSTPRVKPD

11.06

-5.40

-4.97

Q03016

QLPSRTPKKG

8.11

-5.78

-5.35

PPQQLPSRTP

11.12

-5.49

-5.06

SLFSPANPKI

11.49

-5.81

-5.38

Q07807

PMMFMPPPPL

9.69

-8.32

-7.89

FRPSNNPAAV

10.16

-4.26

-3.83

NPMMFMPPPP

10.48

-6.60

-6.17

P40187

EPLNLPNNSA

10.48

-5.41

-4.98

GNPSPPIYKK

10.89

-5.54

-5.11

NGNPSPPIYK

13.92

-4.76

-4.33

P39960

IKFFDPTLPA

11.69

-6.95

-6.52

MLINNPATPN

11.97

-6.90

-6.47

NIKFFDPTLP

12.04

-6.77

-6.34

P26570

MEPKSPILKT

10.82

-7.85

-7.42

TPLNSPGLSK

11.88

-6.42

-5.99

EPKSPILKTN

12.38

-5.39

-4.96

 


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