ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKB-13.PDB
Scoring matrix: BUD14_1CKB-13_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 16.41
Foldx random average score for Saccharomyces cerevisiae: 14.720

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1637195
Proteins after disorder filtering: 4768
 Total fragments: 100965
Proteins after pattern filtering: 2315
 Total fragments: 16175
Proteins after MINT filtering: 13
 Total fragments: 155


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

16.41

-0.90

0.00

Best peptides

HRWLPPFR

0.00

-6.55

-5.65

         
Interactors      
P13186

SIPMSPNY

7.97

-6.36

-5.46

RPPIPAAL

8.74

-4.11

-3.21

IPMSPNYG

9.12

-5.53

-4.63

P27637

YQPLSPPR

8.82

-5.45

-4.55

QPLSPPRE

10.91

-3.67

-2.77

SPSTPIVE

11.90

-3.36

-2.46

Q12276

PQQLPSRK

9.31

-5.34

-4.44

LPSRKPKR

9.98

-5.59

-4.69

PSRKPKRG

12.29

-3.24

-2.34

P38853

PFDTPTIQ

9.76

-4.47

-3.57

PTDTPTPR

12.14

-2.85

-1.95

SAPSPAPK

12.33

-2.38

-1.48

P40095

IPVLPPPR

6.91

-6.84

-5.94

PPPRSPNR

8.86

-5.32

-4.42

NNRIPVLP

10.27

-5.09

-4.19

P40036

LPTTPGIR

7.45

-6.90

-6.00

LPPLSPKS

7.78

-5.53

-4.63

SKSLPTTP

9.87

-4.80

-3.90

P42073

PPREPIEF

10.02

-4.28

-3.38

NKRPPREP

10.92

-4.52

-3.62

RPPREPIE

11.58

-2.76

-1.86

P53858

MTPDSPVK

9.46

-3.09

-2.19

LPEFEPNR

9.95

-4.84

-3.94

KPSPPSSK

10.16

-4.36

-3.46

Q03016

KPQTPILP

9.41

-4.57

-3.67

HPPISSPS

9.53

-3.39

-2.49

SLFSPANP

10.52

-3.02

-2.12

Q07807

MMFMPPPP

8.07

-7.32

-6.42

FMPPPPLS

9.48

-5.17

-4.27

MFMPPPPL

10.12

-4.96

-4.06

P40187

NPSPPIYK

8.31

-5.39

-4.49

GNPSPPIY

8.90

-5.75

-4.85

PLNLPNNS

9.95

-5.88

-4.98

P39960

KFFDPTLP

8.77

-4.41

-3.51

NPATPNQK

10.46

-5.68

-4.78

DPTLPASN

10.97

-5.26

-4.36

P26570

EPKSPILK

8.99

-4.02

-3.12

MEPKSPIL

9.01

-4.25

-3.35

TPSKPNLE

10.57

-4.70

-3.80

 


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