ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKB-11.PDB
Scoring matrix: BUD14_1CKB-11_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 15.42
Foldx random average score for Saccharomyces cerevisiae: 13.909

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 2023571
Proteins after disorder filtering: 4887
 Total fragments: 137384
Proteins after pattern filtering: 2341
 Total fragments: 16015
Proteins after MINT filtering: 13
 Total fragments: 159


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

15.42

-1.01

0.00

Best peptides

RRPFRRQ

0.00

-2.57

-1.56

         
Interactors      
P13186

RPPIPAA

6.81

-6.79

-5.78

IPMSPNY

9.02

-6.51

-5.50

YVPNRVP

9.46

-4.21

-3.20

P27637

PLSPPRE

10.70

-5.38

-4.37

SPSTPIV

10.79

-3.69

-2.68

DPASKPN

11.14

-1.47

-0.46

Q12276

RPKILPK

7.24

-6.60

-5.59

TRPKILP

8.85

-5.49

-4.48

ASPQRPL

9.38

-2.51

-1.50

P38853

PFDTPTI

10.68

-4.38

-3.37

NKPFDTP

11.51

-0.58

0.43

PTDTPTP

12.04

-4.58

-3.57

P40095

RIPVLPP

8.45

-7.78

-6.77

RSPNRPT

8.54

-4.07

-3.06

IPVLPPP

8.75

-7.62

-6.61

P40036

LPTTPGI

10.15

-6.94

-5.93

PPLSPKS

12.07

-4.49

-3.48

LPPLSPK

12.26

-4.86

-3.85

P42073

KRPPREP

7.91

-5.01

-4.00

RPPREPI

7.92

-2.49

-1.48

PPREPIE

9.81

-5.27

-4.26

P53858

PRVKPDS

8.57

-5.26

-4.25

FEPNRPV

9.14

-2.49

-1.48

LPEFEPN

10.51

-4.09

-3.08

Q03016

KPQTPIL

9.28

-5.22

-4.21

NPKILPK

9.48

-6.13

-5.12

KPSRPST

9.53

-3.66

-2.65

Q07807

IPVKMPK

7.54

-5.30

-4.29

FMPPPPL

7.97

-7.13

-6.12

FRPSNNP

8.34

-2.75

-1.74

P40187

NPSPPIY

8.78

-5.09

-4.08

GNPSPPI

10.01

-4.32

-3.31

PLNLPNN

10.78

-6.62

-5.61

P39960

NPATPNQ

8.15

-4.23

-3.22

DPTLPAS

11.53

-5.36

-4.35

FDPTLPA

12.25

-3.99

-2.98

P26570

TPSKPNL

9.00

-4.42

-3.41

DPSTPSK

10.31

-4.93

-3.92

EPKSPIL

10.44

-4.22

-3.21

 


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