ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BUD14_1CKB-1.PDB
Scoring matrix: BUD14_1CKB-1_mat
Uniprot code: P27637
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 25.16
Foldx random average score for Saccharomyces cerevisiae: 26.765

Available information for P27637 in MINT (Nov 2008):
Nš of interacting proteins: 27
 Proteins belonging to other specie: 0
Nš of interactions described: 37
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1719942
Proteins after disorder filtering: 4713
 Total fragments: 154121
Proteins after pattern filtering: 2306
 Total fragments: 21922
Proteins after MINT filtering: 13
 Total fragments: 194


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

25.16

-4.06

0.00

Best peptides

WPRIWWRHRY

0.00

-2.93

1.13

         
Interactors      
P13186

RPPIPAALPP

17.31

-6.79

-2.73

KAPSYVPNRV

17.60

-5.95

-1.89

EPLPEREPPT

17.98

-4.43

-0.37

P27637

QPLSPPRELD

17.11

-5.05

-0.99

DDYQPLSPPR

17.71

-1.83

2.23

NDDYQPLSPP

18.77

-3.38

0.68

Q12276

DPPQQLPSRK

13.51

-6.22

-2.16

ASPQRPLSGQ

16.05

-4.55

-0.49

PPQQLPSRKP

16.88

-7.55

-3.49

P38853

TSNKPFDTPT

16.56

-5.37

-1.31

KPFDTPTIQK

17.53

-6.72

-2.66

VPTDTPTPRN

17.75

-8.04

-3.98

P40095

PPRSPNRPTL

16.05

-5.89

-1.83

LPPPRSPNRP

16.83

-7.67

-3.61

IPVLPPPRSP

17.27

-8.95

-4.89

P40036

KSLPTTPGIR

19.35

-4.72

-0.66

PPLSPKSTVP

19.55

-6.83

-2.77

LPPLSPKSTV

20.53

-7.77

-3.71

P42073

LNKRPPREPI

17.28

-3.47

0.59

RPPREPIEFD

17.61

-5.68

-1.62

KRPPREPIEF

24.99

0.17

4.23

P53858

TPRVKPDSQG

15.76

-5.56

-1.50

KPSPPSSKLY

18.96

-4.94

-0.88

IDSMTPDSPV

19.37

-1.14

2.92

Q03016

DPPQQLPSRT

14.16

-5.35

-1.29

TDNIPLLTPI

15.14

-4.53

-0.47

LPSRTPKKGN

17.16

-4.14

-0.08

Q07807

TPNPIPVKMP

16.43

-6.13

-2.07

NPMMFMPPPP

17.23

-8.34

-4.28

YPTPNPIPVK

17.54

-6.27

-2.21

P40187

ENGNPSPPIY

20.85

-1.80

2.26

GNPSPPIYKK

21.14

-1.84

2.22

MDEPLNLPNN

21.15

-2.29

1.77

P39960

NPATPNQKMR

15.48

-5.95

-1.89

PATPNQKMRD

20.10

-5.23

-1.17

FDPTLPASNS

20.20

0.21

4.27

P26570

TPSKPNLEVN

17.42

-4.81

-0.75

TPLNSPGLSK

19.58

-4.00

0.06

VPDPSTPSKP

20.12

-8.32

-4.26

 


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