ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1SEM-9.PDB
Scoring matrix: BEM1-D2_1SEM-9_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.69
Foldx random average score for Saccharomyces cerevisiae: 12.417

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1459314
Proteins after disorder filtering: 4534
 Total fragments: 69013
Proteins after pattern filtering: 2224
 Total fragments: 13430
Proteins after MINT filtering: 10
 Total fragments: 97


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.69

-1.76

0.00

Best peptides

YPPRPPFD

0.00

-10.98

-9.22

         
Interactors      
P38041

FKLVPPQP

7.24

-8.71

-6.95

RAPKPPSY

7.25

-6.52

-4.76

SPGRAPKP

8.30

-8.51

-6.75

P29366

KRIMPYIP

7.43

-8.90

-7.14

MPYIPGPV

7.64

-8.30

-6.54

YIPGPVPY

9.19

-6.69

-4.93

P21268

KPISPPPS

9.60

-7.34

-5.58

SKPISPPP

10.20

-6.52

-4.76

NLSKPISP

10.27

-6.39

-4.63

P11433

PSATPNME

11.08

-5.96

-4.20

P50090

RIVTPTLP

7.93

-10.23

-8.47

TPTLPPNQ

10.43

-7.84

-6.08

LPWSPESK

10.59

-5.94

-4.18

P32618

NPVISPYS

8.52

-7.05

-5.29

TNPMHPQS

9.38

-4.65

-2.89

GPKVPAKE

9.56

-7.41

-5.65

Q03497

IPSRPAPK

6.05

-8.92

-7.16

LPPIPPTK

7.02

-8.78

-7.02

FPSKNPLK

8.00

-7.18

-5.42

P39969

FKLLPPQP

7.03

-9.59

-7.83

RAPKPPSY

7.25

-6.52

-4.76

SPRRAPKP

7.91

-8.21

-6.45

P22224

FPSTPGTI

8.21

-7.36

-5.60

TPSTPTFP

9.19

-7.88

-6.12

YQSPMTPS

10.70

-5.50

-3.74

P35735

PLASPHFN

11.37

-6.22

-4.46

LASPHFNP

12.29

-4.31

-2.55

SPHFNPQS

12.40

-4.62

-2.86

 


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