ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1SEM-27.PDB
Scoring matrix: BEM1-D2_1SEM-27_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 12.72
Foldx random average score for Saccharomyces cerevisiae: 16.246

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7178
 Total fragments: 1713208
Proteins after disorder filtering: 4734
 Total fragments: 158368
Proteins after pattern filtering: 2304
 Total fragments: 19622
Proteins after MINT filtering: 10
 Total fragments: 136


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

12.72

-1.74

0.00

Best peptides

WHRHLRMWR

0.00

-4.18

-2.44

         
Interactors      
P38041

SPGRAPKPP

7.91

-4.05

-2.31

PGRAPKPPS

9.00

-5.76

-4.02

KPPSYPSPV

9.87

-3.32

-1.58

P29366

YIPGPVPYV

11.11

-3.28

-1.54

KRIMPYIPG

12.68

-5.07

-3.33

PYIPGPVPY

13.65

-1.89

-0.15

P21268

LNLSKPISP

10.76

-2.98

-1.24

KPISPPPSL

12.18

-2.00

-0.26

LSKPISPPP

12.19

-3.65

-1.91

P11433

NPSATPNME

11.66

-4.66

-2.92

SNPSATPNM

12.23

0.35

2.09

NSNPSATPN

12.90

0.04

1.78

P50090

LPWSPESKN

10.95

-4.27

-2.53

ASTALPWSP

12.30

-2.06

-0.32

IVTPTLPPN

13.70

-2.33

-0.59

P32618

YSPSNEPIQ

9.77

-2.31

-0.57

YKANPVISP

10.14

-3.60

-1.86

SPSNEPIQP

11.19

-1.16

0.58

Q03497

FIPSRPAPK

9.21

-4.10

-2.36

IPSRPAPKP

9.41

-4.72

-2.98

SRPAPKPPS

9.65

-4.40

-2.66

P39969

SPRRAPKPP

6.20

-5.27

-3.53

VSPRRAPKP

8.54

-1.30

0.44

PRRAPKPPS

8.58

-5.52

-3.78

P22224

MTPSTPTFP

9.44

-2.45

-0.71

GYQSPMTPS

11.66

-3.80

-2.06

IFPSTPGTI

12.94

-0.43

1.31

P35735

ASPHFNPQS

9.90

-1.94

-0.20

PHFNPQSSE

12.31

-1.92

-0.18

SPHFNPQSS

12.60

-1.72

0.02

 


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