ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1SEM-26.PDB
Scoring matrix: BEM1-D2_1SEM-26_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.15
Foldx random average score for Saccharomyces cerevisiae: 13.043

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1286421
Proteins after disorder filtering: 4339
 Total fragments: 65470
Proteins after pattern filtering: 2189
 Total fragments: 15064
Proteins after MINT filtering: 10
 Total fragments: 120


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

17.15

-1.89

0.00

Best peptides

SERPRMFRR

0.00

-7.20

-5.31

         
Interactors      
P38041

PQSPSFNNR

8.27

-5.95

-4.06

GRAPKPPSY

9.05

-6.13

-4.24

FESPGRAPK

9.17

-5.76

-3.87

P29366

RIMPYIPGP

9.30

-7.70

-5.81

PYIPGPVPY

10.83

-4.34

-2.45

KRIMPYIPG

11.50

-4.53

-2.64

P21268

SKPISPPPS

9.19

-5.78

-3.89

KPISPPPSL

10.73

-4.76

-2.87

PISPPPSLK

11.39

-2.78

-0.89

P11433

SNPSATPNM

10.93

-6.25

-4.36

P50090

PTLPPNQHR

9.57

-6.41

-4.52

ALPWSPESK

9.96

-0.60

1.29

VTPTLPPNQ

11.72

-5.02

-3.13

P32618

PSPKPSHKR

6.48

-6.00

-4.11

KEPSPKPSH

8.76

-6.10

-4.21

NDVPIVPGN

8.94

-7.29

-5.40

Q03497

HKPKVKPSK

5.85

-6.20

-4.31

THAPTTPNR

6.70

-7.37

-5.48

PLPPIPPTK

7.18

-6.54

-4.65

P39969

LSPIPSPTR

6.01

-7.71

-5.82

RRAPKPPSY

8.27

-6.35

-4.46

YPSPAQPPK

8.68

-5.66

-3.77

P22224

STPTFPNAN

10.65

-3.66

-1.77

TPSTPTFPN

10.76

-4.96

-3.07

PMTPSTPTF

11.94

-6.72

-4.83

P35735

PLASPHFNP

12.27

-4.37

-2.48

LASPHFNPQ

12.49

-2.56

-0.67

ASPHFNPQS

12.88

-3.92

-2.03

 


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