ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1SEM-18.PDB
Scoring matrix: BEM1-D2_1SEM-18_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 24.3
Foldx random average score for Saccharomyces cerevisiae: 19.251

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1455958
Proteins after disorder filtering: 4386
 Total fragments: 67582
Proteins after pattern filtering: 1964
 Total fragments: 8326
Proteins after MINT filtering: 8
 Total fragments: 66


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

24.30

0.87

0.00

Best peptides

RWPLNSRMYY

0.00

-1.98

-2.85

         
Interactors      
P38041

IFESPGRAPK

15.02

-0.67

-1.54

PPQPGSKKGL

15.06

-2.70

-3.57

VPPQPGSKKG

15.23

-4.51

-5.38

P29366

MPYIPGPVPY

11.44

-3.56

-4.43

KRIMPYIPGP

17.28

-6.19

-7.06

P50090

TPTLPPNQHR

14.28

-3.67

-4.54

RIVTPTLPPN

17.23

-2.13

-3.00

TALPWSPESK

19.06

0.17

-0.70

P32618

PAPLPSHYSS

12.34

-2.92

-3.79

VPNLSPRLSN

13.30

-4.04

-4.91

PSPKPSHKRN

14.01

-4.27

-5.14

Q03497

KKSFPSKNPL

12.62

-0.63

-1.50

LPPIPPTKSK

12.79

-3.53

-4.40

KQHKPKVKPS

13.71

-6.57

-7.44

P39969

LPPQPGSKKG

13.85

-5.39

-6.26

PPQPGSKKGL

15.06

-2.70

-3.57

FKLLPPQPGS

15.97

-5.38

-6.25

P22224

FPSTPGTIDS

15.57

-2.43

-3.30

TPTFPNANGV

18.60

-2.77

-3.64

P35735

PLASPHFNPQ

16.34

0.35

-0.52

ASPHFNPQSS

18.52

-1.31

-2.18

SPHFNPQSSE

18.83

-0.26

-1.13

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER