ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1GCQ-7.PDB
Scoring matrix: BEM1-D2_1GCQ-7_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 13.74
Foldx random average score for Saccharomyces cerevisiae: 11.744

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1344621
Proteins after disorder filtering: 4428
 Total fragments: 57703
Proteins after pattern filtering: 1987
 Total fragments: 8324
Proteins after MINT filtering: 10
 Total fragments: 74


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

13.74

1.39

0.00

Best peptides

WRRRRPWE

0.00

0.22

-1.17

         
Interactors      
P38041

RAPKPPSY

10.16

-3.62

-5.01

PKPPSYPS

10.39

-0.72

-2.11

PSPVQPPQ

10.46

-1.92

-3.31

P29366

KRIMPYIP

9.56

-6.01

-7.40

MPYIPGPV

11.20

-4.27

-5.66

RIMPYIPG

11.40

-3.16

-4.55

P21268

SKPISPPP

10.69

-1.93

-3.32

P11433

PSATPNME

11.17

-5.86

-7.25

P50090

PWSPESKN

10.13

-2.65

-4.04

VTPTLPPN

10.24

-4.30

-5.69

ALPWSPES

10.65

-0.25

-1.64

P32618

KSEPAPLP

9.46

-3.79

-5.18

NPVISPYS

9.62

-4.25

-5.64

VPNLSPRL

9.81

-4.08

-5.47

Q03497

FPSKNPLK

7.58

-4.42

-5.81

KVKPSKPE

9.06

-1.46

-2.85

KPKVKPSK

9.14

-2.99

-4.38

P39969

QPPKSPLL

6.71

-3.53

-4.92

VSPRRAPK

8.04

-3.95

-5.34

RRAPKPPS

8.74

-1.57

-2.96

P22224

YQSPMTPS

10.82

-2.00

-3.39

PMTPSTPT

11.72

-1.31

-2.70

P35735

ASPHFNPQ

10.65

-2.93

-4.32

PLASPHFN

10.80

-4.79

-6.18

 


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