ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1GCQ-27.PDB
Scoring matrix: BEM1-D2_1GCQ-27_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 16.21
Foldx random average score for Saccharomyces cerevisiae: 16.556

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1606931
Proteins after disorder filtering: 4687
 Total fragments: 108739
Proteins after pattern filtering: 2250
 Total fragments: 14684
Proteins after MINT filtering: 10
 Total fragments: 102


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

16.21

0.98

0.00

Best peptides

RDKFMRIRR

0.00

6.49

5.51

         
Interactors      
P38041

PGRAPKPPS

10.40

-4.03

-5.01

RAPKPPSYP

10.80

-4.72

-5.70

SPGRAPKPP

11.71

-2.18

-3.16

P29366

IMPYIPGPV

9.91

-2.20

-3.18

YIPGPVPYV

13.42

-3.13

-4.11

KRIMPYIPG

14.89

-2.97

-3.95

P21268

LNLSKPISP

12.52

-1.97

-2.95

LSKPISPPP

13.53

-2.84

-3.82

KPISPPPSL

14.07

-1.94

-2.92

P11433

NPSATPNME

15.15

-1.72

-2.70

TNSNPSATP

15.67

-1.20

-2.18

SNPSATPNM

15.73

-0.25

-1.23

P50090

LPWSPESKN

13.15

-2.00

-2.98

ASTALPWSP

15.27

-0.43

-1.41

IVTPTLPPN

16.37

-2.16

-3.14

P32618

PSTSPSGRR

12.07

-3.19

-4.17

YKANPVISP

12.60

-0.72

-1.70

YSPSNEPIQ

12.85

-1.54

-2.52

Q03497

NGKFIPSRP

6.50

-2.54

-3.52

KKSFPSKNP

9.50

-2.17

-3.15

IPSRPAPKP

10.93

-2.53

-3.51

P39969

SPRRAPKPP

10.26

-1.40

-2.38

PRRAPKPPS

10.78

-4.66

-5.64

RAPKPPSYP

10.80

-4.72

-5.70

P22224

TPTFPNANG

11.96

-0.88

-1.86

GYQSPMTPS

12.80

-1.54

-2.52

MTPSTPTFP

13.56

-2.36

-3.34

P35735

SPHFNPQSS

11.60

0.46

-0.52

ASPHFNPQS

13.16

-2.43

-3.41

PHFNPQSSE

15.08

-0.50

-1.48

 


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