ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1GCQ-25.PDB
Scoring matrix: BEM1-D2_1GCQ-25_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.9
Foldx random average score for Saccharomyces cerevisiae: 15.571

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1703916
Proteins after disorder filtering: 4613
 Total fragments: 114557
Proteins after pattern filtering: 2303
 Total fragments: 20157
Proteins after MINT filtering: 10
 Total fragments: 141


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

17.90

3.67

0.00

Best peptides

KYPPIGGRP

0.00

-3.37

-7.04

         
Interactors      
P38041

VPPQPGSKK

8.18

-3.78

-7.45

CFKLVPPQP

8.23

-4.65

-8.32

IFESPGRAP

8.34

-2.72

-6.39

P29366

IMPYIPGPV

8.29

-4.03

-7.70

MPYIPGPVP

9.98

-1.10

-4.77

PYIPGPVPY

10.86

-3.22

-6.89

P21268

LSKPISPPP

10.40

-2.06

-5.73

PISPPPSLK

10.95

-2.62

-6.29

LNLSKPISP

11.60

-2.73

-6.40

P11433

NPSATPNME

13.98

-2.84

-6.51

P50090

VTPTLPPNQ

11.78

-6.61

-10.28

ALPWSPESK

11.84

-2.74

-6.41

ASTALPWSP

12.08

-2.74

-6.41

P32618

EPAPLPSHY

9.89

-4.38

-8.05

EPSPKPSHK

10.02

-3.37

-7.04

SKSEPAPLP

11.40

-2.16

-5.83

Q03497

SFPSKNPLK

7.69

-4.66

-8.33

NGKFIPSRP

7.79

-5.40

-9.07

KPKVKPSKP

8.15

-2.26

-5.93

P39969

CFKLLPPQP

7.33

-7.01

-10.68

LPPQPGSKK

8.05

-3.16

-6.83

LLPPQPGSK

9.38

-3.43

-7.10

P22224

MTPSTPTFP

10.59

-4.91

-8.58

STPTFPNAN

11.85

-0.93

-4.60

FPSTPGTID

12.50

-0.67

-4.34

P35735

ASPHFNPQS

13.15

0.00

-3.67

LASPHFNPQ

13.93

1.70

-1.97

PLASPHFNP

13.95

0.50

-3.17

 


    Comments or questions on the site? Send a mail to adandatabase@umh.es                                                     
DISCLAIMER