ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1GCQ-18.PDB
Scoring matrix: BEM1-D2_1GCQ-18_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 20.24
Foldx random average score for Saccharomyces cerevisiae: 18.974

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1452110
Proteins after disorder filtering: 4481
 Total fragments: 79759
Proteins after pattern filtering: 2033
 Total fragments: 9225
Proteins after MINT filtering: 9
 Total fragments: 71


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

20.24

0.13

0.00

Best peptides

FPPLNSRRWY

0.00

-0.46

-0.59

         
Interactors      
P38041

PPQSPSFNNR

13.73

-1.98

-2.11

IFESPGRAPK

15.69

-2.22

-2.35

PPQPGSKKGL

16.29

-3.12

-3.25

P29366

MPYIPGPVPY

11.36

-4.25

-4.38

KRIMPYIPGP

17.06

-5.64

-5.77

P11433

TNSNPSATPN

18.73

-0.74

-0.87

P50090

TPTLPPNQHR

13.28

-3.49

-3.62

TALPWSPESK

18.39

1.11

0.98

RIVTPTLPPN

18.62

-4.89

-5.02

P32618

PAPLPSHYSS

11.81

-4.66

-4.79

PSPKPSHKRN

13.88

-3.02

-3.15

PSTSPSGRRM

13.96

0.01

-0.12

Q03497

FPSKNPLKNS

11.83

-5.35

-5.48

KPSKPEAKSK

13.87

-3.33

-3.46

LPPIPPTKSK

14.14

-3.87

-4.00

P39969

QPPKSPLLNN

14.29

-4.30

-4.43

LSPIPSPTRN

14.89

-5.40

-5.53

LPPQPGSKKG

15.56

-2.70

-2.83

P22224

FPSTPGTIDS

14.27

-2.06

-2.19

TPSTPTFPNA

17.81

-0.29

-0.42

TPTFPNANGV

18.12

-2.43

-2.56

P35735

ASPHFNPQSS

18.25

-0.95

-1.08

SPHFNPQSSE

18.27

-0.58

-0.71

PLASPHFNPQ

18.80

-2.33

-2.46

 


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