ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D2_1GCQ-14.PDB
Scoring matrix: BEM1-D2_1GCQ-14_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 18.29
Foldx random average score for Saccharomyces cerevisiae: 14.120

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1376604
Proteins after disorder filtering: 4215
 Total fragments: 51800
Proteins after pattern filtering: 1817
 Total fragments: 6303
Proteins after MINT filtering: 8
 Total fragments: 45


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

18.29

-4.30

0.00

Best peptides

IPFMRHRLR

0.00

-9.06

-4.76

         
Interactors      
P38041

PQSPSFNNR

10.74

-6.94

-2.64

QPPQSPSFN

11.43

-4.55

-0.25

PPSYPSPVQ

12.22

-5.82

-1.52

P29366

KRIMPYIPG

10.32

-7.19

-2.89

IMPYIPGPV

11.23

-5.72

-1.42

IPGPVPYVT

13.05

-5.80

-1.50

P50090

PTLPPNQHR

12.66

-8.29

-3.99

LPWSPESKN

13.16

-3.82

0.48

VTPTLPPNQ

13.61

-4.31

-0.01

P32618

PSPKPSHKR

9.07

-8.48

-4.18

TPSTSPSGR

11.08

-9.18

-4.88

VPNLSPRLS

11.94

-8.11

-3.81

Q03497

FPSKNPLKN

9.56

-6.32

-2.02

HKPKVKPSK

12.04

-6.95

-2.65

LPPIPPTKS

12.40

-8.54

-4.24

P39969

QPPKSPLLN

8.98

-6.89

-2.59

LSPIPSPTR

10.75

-9.96

-5.66

PEENPITSM

12.51

-7.01

-2.71

P22224

TPSTPTFPN

13.74

-6.44

-2.14

TPTFPNANG

13.78

-5.96

-1.66

IFPSTPGTI

13.82

-6.46

-2.16

P35735

LASPHFNPQ

12.44

-5.57

-1.27

 


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