ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-8.PDB
Scoring matrix: BEM1-D1_JO8-QCF-8_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.68
Foldx random average score for Saccharomyces cerevisiae: 12.312

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1613313
Proteins after disorder filtering: 4777
 Total fragments: 132120
Proteins after pattern filtering: 2301
 Total fragments: 17875
Proteins after MINT filtering: 10
 Total fragments: 128


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

14.68

-0.92

0.00

Best peptides

DRRFLSPM

0.00

-0.25

0.67

         
Interactors      
P38041

GRAPKPPS

6.91

-5.46

-4.54

VQPPQSPS

7.49

-3.28

-2.36

VPPQPGSK

7.75

-4.81

-3.89

P29366

IMPYIPGP

6.73

-7.48

-6.56

KRIMPYIP

8.78

-3.19

-2.27

MPYIPGPV

9.58

-2.71

-1.79

P21268

LSKPISPP

7.02

-3.51

-2.59

SKPISPPP

8.68

-6.64

-5.72

KPISPPPS

9.51

-4.89

-3.97

P11433

NPSATPNM

9.72

-5.15

-4.23

P50090

PWSPESKN

7.79

-0.21

0.71

VTPTLPPN

9.02

-5.26

-4.34

TALPWSPE

9.30

-1.88

-0.96

P32618

PSPKPSHK

7.42

-2.02

-1.10

ANPVISPY

7.77

-2.94

-2.02

VGPKVPAK

8.83

-5.65

-4.73

Q03497

EEQPLPPI

6.98

-5.72

-4.80

SRPAPKPP

7.48

-4.84

-3.92

PSRPAPKP

7.55

-4.00

-3.08

P39969

AQPPKSPL

5.56

-4.40

-3.48

PRRAPKPP

5.88

-3.71

-2.79

RRAPKPPS

6.86

-5.24

-4.32

P22224

SPMTPSTP

9.73

-2.40

-1.48

IFPSTPGT

9.78

-3.54

-2.62

QSPMTPST

9.87

-3.24

-2.32

P35735

ASPHFNPQ

9.52

-2.70

-1.78

SPHFNPQS

10.78

-4.18

-3.26

LASPHFNP

12.07

-3.10

-2.18

 


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