ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-28.PDB
Scoring matrix: BEM1-D1_JO8-QCF-28_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.15
Foldx random average score for Saccharomyces cerevisiae: 17.516

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1751145
Proteins after disorder filtering: 4465
 Total fragments: 83873
Proteins after pattern filtering: 2151
 Total fragments: 13510
Proteins after MINT filtering: 10
 Total fragments: 105


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

20.15

-2.09

0.00

Best peptides

RRPRPPRKNK

0.00

-8.73

-6.64

         
Interactors      
P38041

LVPPQPGSKK

10.53

-10.57

-8.48

KLVPPQPGSK

10.55

-9.18

-7.09

PPQSPSFNNR

12.00

-10.44

-8.35

P29366

YIPGPVPYVT

13.72

-10.00

-7.91

PYIPGPVPYV

16.49

-7.12

-5.03

P21268

KPISPPPSLK

9.35

-10.02

-7.93

PISPPPSLKK

11.08

-10.87

-8.78

SKPISPPPSL

15.28

-7.88

-5.79

P11433

NSNPSATPNM

15.24

-7.93

-5.84

P50090

IVTPTLPPNQ

13.03

-9.28

-7.19

TPTLPPNQHR

13.72

-11.55

-9.46

PTLPPNQHRG

16.41

-10.39

-8.30

P32618

KEPSPKPSHK

11.25

-8.96

-6.87

VPIVPGNNTT

12.91

-10.96

-8.87

EPSPKPSHKR

12.97

-13.27

-11.18

Q03497

KPSKPEAKSK

8.22

-8.98

-6.89

LPPIPPTKSK

8.33

-10.34

-8.25

QPLPPIPPTK

8.98

-10.99

-8.90

P39969

PIPSPTRNSV

10.41

-10.70

-8.61

KLLPPQPGSK

10.46

-9.82

-7.73

LLPPQPGSKK

10.93

-9.69

-7.60

P22224

TPSTPTFPNA

13.12

-9.62

-7.53

FPSTPGTIDS

15.02

-7.76

-5.67

TPTFPNANGV

15.95

-7.82

-5.73

P35735

PHFNPQSSEK

14.06

-7.44

-5.35

SPHFNPQSSE

15.40

-7.79

-5.70

LASPHFNPQS

17.28

-9.30

-7.21

 


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