ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-26.PDB
Scoring matrix: BEM1-D1_JO8-QCF-26_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 12.46
Foldx random average score for Saccharomyces cerevisiae: 11.659

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1713806
Proteins after disorder filtering: 4651
 Total fragments: 119525
Proteins after pattern filtering: 2293
 Total fragments: 21727
Proteins after MINT filtering: 10
 Total fragments: 161


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

12.46

-1.35

0.00

Best peptides

SDPHRMKPR

0.00

-3.33

-1.99

         
Interactors      
P38041

GRAPKPPSY

6.38

-6.96

-5.62

KLVPPQPGS

6.71

-6.87

-5.53

LVPPQPGSK

6.92

-5.90

-4.56

P29366

RIMPYIPGP

5.84

-8.71

-7.37

PYIPGPVPY

7.07

-5.41

-4.07

IMPYIPGPV

9.75

-4.12

-2.78

P21268

SKPISPPPS

6.79

-6.60

-5.25

PISPPPSLK

6.85

-5.12

-3.78

LSKPISPPP

7.35

-6.73

-5.39

P11433

NSNPSATPN

8.09

-3.69

-2.34

SNPSATPNM

9.04

-5.40

-4.06

P50090

ALPWSPESK

8.29

-4.04

-2.70

PTLPPNQHR

8.38

-6.52

-5.17

VTPTLPPNQ

9.08

-5.24

-3.90

P32618

NDVPIVPGN

6.24

-7.47

-6.13

KANPVISPY

6.68

-5.92

-4.58

KEPSPKPSH

6.68

-6.07

-4.73

Q03497

PLPPIPPTK

4.71

-8.43

-7.09

PSKPEAKSK

5.50

-6.51

-5.17

HKPKVKPSK

5.80

-7.48

-6.14

P39969

RRAPKPPSY

5.27

-7.14

-5.79

SPRRAPKPP

6.06

-5.61

-4.27

LSPIPSPTR

6.21

-6.08

-4.74

P22224

QSPMTPSTP

8.21

-4.91

-3.57

NGYQSPMTP

9.37

-5.61

-4.27

PMTPSTPTF

9.74

-5.60

-4.25

P35735

ASPHFNPQS

7.20

-5.31

-3.96

SPHFNPQSS

8.42

-4.10

-2.75

PHFNPQSSE

9.03

-3.21

-1.87

 


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