ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-23.PDB
Scoring matrix: BEM1-D1_JO8-QCF-23_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 9.38
Foldx random average score for Saccharomyces cerevisiae: 10.552

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1650573
Proteins after disorder filtering: 4924
 Total fragments: 158146
Proteins after pattern filtering: 2278
 Total fragments: 14492
Proteins after MINT filtering: 10
 Total fragments: 98


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

9.38

-1.06

0.00

Best peptides

RPRMPRP

0.00

-1.20

-0.14

         
Interactors      
P38041

RAPKPPS

5.29

-2.25

-1.19

PGRAPKP

6.18

-4.07

-3.01

QPPQSPS

6.45

-2.81

-1.75

P29366

YIPGPVP

6.98

-2.63

-1.57

IPGPVPY

8.77

-2.33

-1.27

RIMPYIP

9.57

-7.34

-6.28

P21268

KPISPPP

9.20

-4.58

-3.52

PISPPPS

9.86

-2.92

-1.86

P11433

NPSATPN

7.03

-2.56

-1.50

SNPSATP

8.79

-2.54

-1.48

P50090

LPWSPES

8.13

-2.12

-1.06

PWSPESK

9.24

-3.53

-2.47

P32618

KEPSPKP

5.82

-3.47

-2.41

KVPAKEP

6.05

-4.10

-3.04

SEPAPLP

6.31

-3.79

-2.73

Q03497

HKPKVKP

5.06

-2.56

-1.50

IPSRPAP

5.67

-3.29

-2.23

RPAPKPP

6.24

-4.44

-3.38

P39969

RAPKPPS

5.29

-2.25

-1.19

PRRAPKP

5.78

-4.96

-3.90

LPPQPGS

5.80

-3.25

-2.19

P22224

QSPMTPS

6.46

-3.70

-2.64

MTPSTPT

7.33

-3.19

-2.13

IFPSTPG

8.59

-2.21

-1.15

P35735

ASPHFNP

7.28

-1.35

-0.29

PHFNPQS

8.19

-1.13

-0.07

PLASPHF

8.21

-2.02

-0.96

 


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