ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-21.PDB
Scoring matrix: BEM1-D1_JO8-QCF-21_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 18.47
Foldx random average score for Saccharomyces cerevisiae: 16.118

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 2020521
Proteins after disorder filtering: 4421
 Total fragments: 70522
Proteins after pattern filtering: 1698
 Total fragments: 4284
Proteins after MINT filtering: 7
 Total fragments: 30


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

18.47

-0.58

0.00

Best peptides

EWILGRPTMH

0.00

-1.54

-0.96

         
Interactors      
P38041

QSNPTSPTKQ

10.16

-5.85

-5.27

PTSPTKQTFT

10.84

-4.53

-3.95

PQSPSFNNRY

12.40

-3.55

-2.97

P11433

SNPSATPNME

13.77

-5.43

-4.85

P50090

VTPTLPPNQH

11.29

-3.65

-3.07

P32618

PIVPGNNTTL

11.33

-4.83

-4.25

EPSPKPSHKR

11.50

-4.27

-3.69

EPAPLPSHYS

14.78

-4.11

-3.53

Q03497

THAPTTPNRT

12.87

-3.83

-3.25

PLPPIPPTKS

13.40

-4.59

-4.01

TGLPGSPQVS

13.57

-2.10

-1.52

P39969

AQPPKSPLLN

13.29

-5.68

-5.10

PKSPLLNNTR

13.73

-4.84

-4.26

PPQPGSKKGL

14.41

-3.13

-2.55

P22224

PSTPTFPNAN

14.96

-2.44

-1.86

PTFPNANGVD

15.28

-2.57

-1.99

 


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