ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-19.PDB
Scoring matrix: BEM1-D1_JO8-QCF-19_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.73
Foldx random average score for Saccharomyces cerevisiae: 16.031

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1594176
Proteins after disorder filtering: 4648
 Total fragments: 102049
Proteins after pattern filtering: 2253
 Total fragments: 12806
Proteins after MINT filtering: 10
 Total fragments: 96


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.73

-0.72

0.00

Best peptides

YRTRPGRSF

0.00

-1.47

-0.75

         
Interactors      
P38041

IFESPGRAP

10.00

-6.37

-5.65

VPPQPGSKK

10.17

-6.93

-6.21

PTSPTKQTF

11.57

-5.34

-4.62

P29366

KRIMPYIPG

12.71

-5.09

-4.37

MPYIPGPVP

13.50

-6.15

-5.43

YIPGPVPYV

14.24

-4.55

-3.83

P21268

NLSKPISPP

14.99

-7.18

-6.46

P11433

SNPSATPNM

13.56

-5.27

-4.55

TNSNPSATP

15.06

-4.68

-3.96

P50090

PTLPPNQHR

10.81

-10.11

-9.39

IVTPTLPPN

13.06

-5.81

-5.09

RIVTPTLPP

13.53

-5.82

-5.10

P32618

VPIVPGNNT

11.27

-5.11

-4.39

DSSTPSTSP

11.60

-5.57

-4.85

KEPSPKPSH

11.73

-7.51

-6.79

Q03497

PPIPPTKSK

8.88

-8.11

-7.39

HKPKVKPSK

10.26

-3.80

-3.08

APTTPNRTS

10.29

-3.46

-2.74

P39969

LPPQPGSKK

9.85

-6.25

-5.53

YPSPAQPPK

10.69

-5.80

-5.08

PIPSPTRNS

11.90

-4.89

-4.17

P22224

FPSTPGTID

10.35

-4.71

-3.99

PMTPSTPTF

11.75

-6.61

-5.89

YQSPMTPST

12.38

-6.45

-5.73

P35735

PLASPHFNP

12.28

-6.37

-5.65

LASPHFNPQ

15.87

-5.11

-4.39

 


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