ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-13.PDB
Scoring matrix: BEM1-D1_JO8-QCF-13_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.75
Foldx random average score for Saccharomyces cerevisiae: 14.602

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1531828
Proteins after disorder filtering: 4805
 Total fragments: 102999
Proteins after pattern filtering: 2268
 Total fragments: 14150
Proteins after MINT filtering: 10
 Total fragments: 112


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.75

0.76

0.00

Best peptides

RHPRGPRW

0.00

-2.27

-3.02

         
Interactors      
P38041

SPGRAPKP

7.27

-6.32

-7.08

PPQPGSKK

9.82

-3.47

-4.23

QPPQSPSF

10.53

-2.94

-3.69

P29366

KRIMPYIP

10.48

-7.08

-7.84

MPYIPGPV

10.55

-6.64

-7.39

PYIPGPVP

12.07

-3.19

-3.94

P21268

SKPISPPP

12.16

-3.40

-4.16

KPISPPPS

12.67

-6.03

-6.79

NLSKPISP

12.92

-5.11

-5.87

P11433

PSATPNME

13.57

-5.02

-5.77

NSNPSATP

13.62

-0.24

-1.00

P50090

RIVTPTLP

9.73

-6.15

-6.91

TPTLPPNQ

12.53

-7.19

-7.95

ALPWSPES

12.78

-0.98

-1.73

P32618

VPNLSPRL

5.91

-6.96

-7.71

NPVISPYS

9.66

-3.53

-4.29

GPKVPAKE

10.32

-5.91

-6.67

Q03497

IPSRPAPK

8.77

-6.06

-6.81

GKFIPSRP

8.87

-7.49

-8.25

APTTPNRT

9.80

-7.86

-8.62

P39969

SPRRAPKP

6.81

-5.77

-6.52

QPPKSPLL

7.40

-5.19

-5.95

PPQPGSKK

9.82

-3.47

-4.23

P22224

PSTPGTID

11.86

-2.43

-3.19

TPSTPTFP

13.54

-6.00

-6.75

FPSTPGTI

13.54

-4.79

-5.54

P35735

SPHFNPQS

13.33

-4.20

-4.96

PHFNPQSS

13.55

-3.53

-4.29

ASPHFNPQ

14.42

-2.22

-2.98

 


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