ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-QCF-12.PDB
Scoring matrix: BEM1-D1_JO8-QCF-12_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 10.95
Foldx random average score for Saccharomyces cerevisiae: 10.744

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1651771
Proteins after disorder filtering: 4755
 Total fragments: 98900
Proteins after pattern filtering: 2189
 Total fragments: 9442
Proteins after MINT filtering: 10
 Total fragments: 71


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

10.95

-0.48

0.00

Best peptides

YEFRPKFK

0.00

-1.86

-1.38

         
Interactors      
P38041

PGRAPKPP

5.63

-3.09

-2.61

PSPVQPPQ

8.10

-2.69

-2.21

FKLVPPQP

8.37

-2.43

-1.95

P29366

YIPGPVPY

8.37

-3.48

-3.00

MPYIPGPV

9.35

-2.82

-2.34

PGPVPYVT

9.46

-3.65

-3.17

P21268

SKPISPPP

6.81

-2.70

-2.22

NLSKPISP

9.36

-2.62

-2.14

P11433

SNPSATPN

9.86

-2.18

-1.70

P50090

ALPWSPES

10.11

-2.24

-1.76

VTPTLPPN

10.62

-2.03

-1.55

P32618

KEPSPKPS

4.85

-4.00

-3.52

SEPAPLPS

4.92

-4.87

-4.39

NEPIQPSS

7.43

-2.71

-2.23

Q03497

SRPAPKPP

4.11

-3.94

-3.46

HKPKVKPS

6.14

-4.34

-3.86

GKFIPSRP

7.62

-2.69

-2.21

P39969

PRRAPKPP

4.59

-3.94

-3.46

VSPRRAPK

5.98

-3.10

-2.62

PSPAQPPK

7.34

-2.82

-2.34

P22224

GYQSPMTP

8.90

-4.35

-3.87

MTPSTPTF

9.68

-2.15

-1.67

IFPSTPGT

9.74

-2.46

-1.98

P35735

ASPHFNPQ

7.43

-2.68

-2.20

PLASPHFN

7.83

-3.99

-3.51

PHFNPQSS

8.27

-3.25

-2.77

 


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