ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-8.PDB
Scoring matrix: BEM1-D1_JO8-LCK-8_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 10.48
Foldx random average score for Saccharomyces cerevisiae: 12.415

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1506065
Proteins after disorder filtering: 4803
 Total fragments: 148254
Proteins after pattern filtering: 2341
 Total fragments: 21121
Proteins after MINT filtering: 10
 Total fragments: 158


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

10.48

-3.30

0.00

Best peptides

DRNFWFPM

0.00

3.44

6.74

         
Interactors      
P38041

RAPKPPSY

5.38

-4.54

-1.24

FKLVPPQP

5.74

-5.21

-1.91

PKPPSYPS

5.92

-5.09

-1.79

P29366

KRIMPYIP

4.95

-4.58

-1.28

IMPYIPGP

7.60

-8.77

-5.47

MPYIPGPV

8.03

-2.79

0.51

P21268

SKPISPPP

5.08

-5.29

-1.99

KPISPPPS

6.89

-6.05

-2.75

PISPPPSL

8.44

-3.86

-0.56

P11433

SNPSATPN

8.28

-3.28

0.02

NSNPSATP

8.88

-2.57

0.73

PSATPNME

10.63

-1.06

2.24

P50090

TALPWSPE

7.15

-3.34

-0.04

TPTLPPNQ

8.46

-3.89

-0.59

LPWSPESK

8.88

-1.36

1.94

P32618

VPNLSPRL

5.80

-5.32

-2.02

SEPAPLPS

6.16

-3.49

-0.19

KEPSPKPS

6.25

-3.48

-0.18

Q03497

SRPAPKPP

3.22

-6.18

-2.88

LPPIPPTK

6.02

-7.26

-3.96

EQPLPPIP

6.26

-6.41

-3.11

P39969

PRRAPKPP

3.42

-2.48

0.82

RAPKPPSY

5.38

-4.54

-1.24

SPRRAPKP

5.72

-5.44

-2.14

P22224

SPMTPSTP

7.67

-2.85

0.45

TPSTPTFP

8.26

-2.44

0.86

FPSTPGTI

8.96

-3.08

0.22

P35735

PHFNPQSS

10.20

-2.33

0.97

SPHFNPQS

11.62

-5.40

-2.10

PLASPHFN

11.84

-2.97

0.33

 


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