ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-7.PDB
Scoring matrix: BEM1-D1_JO8-LCK-7_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 15.52
Foldx random average score for Saccharomyces cerevisiae: 12.435

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1255560
Proteins after disorder filtering: 4672
 Total fragments: 74270
Proteins after pattern filtering: 2190
 Total fragments: 12374
Proteins after MINT filtering: 10
 Total fragments: 87


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

15.52

-3.54

0.00

Best peptides

FMPGPPRW

0.00

-0.03

3.51

         
Interactors      
P38041

FKLVPPQP

8.98

-7.60

-4.06

RAPKPPSY

9.97

-5.36

-1.82

ESPGRAPK

9.99

-2.82

0.72

P29366

YIPGPVPY

6.25

-5.20

-1.66

MPYIPGPV

8.63

-6.96

-3.42

KRIMPYIP

9.15

-7.22

-3.68

P21268

KPISPPPS

11.18

-5.32

-1.78

NLSKPISP

11.34

-5.81

-2.27

PISPPPSL

11.54

-5.60

-2.06

P11433

PSATPNME

10.29

-6.46

-2.92

NPSATPNM

12.31

-2.30

1.24

P50090

TPTLPPNQ

10.40

-5.27

-1.73

RIVTPTLP

11.43

-6.97

-3.43

ALPWSPES

11.78

-3.16

0.38

P32618

VPNLSPRL

10.24

-5.25

-1.71

GPKVPAKE

10.71

-5.43

-1.89

PAPLPSHY

10.82

-4.91

-1.37

Q03497

FPSKNPLK

6.92

-7.56

-4.02

GKFIPSRP

8.98

-7.56

-4.02

APTTPNRT

9.23

-6.07

-2.53

P39969

FKLLPPQP

8.79

-7.70

-4.16

PIPSPTRN

9.25

-6.37

-2.83

RAPKPPSY

9.97

-5.36

-1.82

P22224

FPSTPGTI

9.68

-6.58

-3.04

TPTFPNAN

10.26

-3.15

0.39

YQSPMTPS

10.27

-4.78

-1.24

P35735

SPHFNPQS

10.11

-3.35

0.19

PLASPHFN

11.68

-5.11

-1.57

 


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