ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-5.PDB
Scoring matrix: BEM1-D1_JO8-LCK-5_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 21.84
Foldx random average score for Saccharomyces cerevisiae: 27.342

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1466185
Proteins after disorder filtering: 4584
 Total fragments: 100369
Proteins after pattern filtering: 2300
 Total fragments: 20328
Proteins after MINT filtering: 10
 Total fragments: 139


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

21.84

1.10

0.00

Best peptides

RRNYPAGDIP

0.00

-0.29

-1.39

         
Interactors      
P38041

LVPPQPGSKK

14.64

-2.31

-3.41

GRAPKPPSYP

15.48

-7.14

-8.24

RAPKPPSYPS

16.74

-5.50

-6.60

P29366

IMPYIPGPVP

10.49

-4.71

-5.81

KRIMPYIPGP

18.72

-6.39

-7.49

MPYIPGPVPY

20.92

-7.50

-8.60

P21268

LNLSKPISPP

19.48

-6.78

-7.88

KPISPPPSLK

20.23

-7.47

-8.57

PISPPPSLKK

20.59

-3.68

-4.78

P11433

YTNSNPSATP

20.44

-4.56

-5.66

NSNPSATPNM

24.17

-3.18

-4.28

P50090

ASTALPWSPE

19.27

-4.35

-5.45

ALPWSPESKN

19.64

-4.86

-5.96

VTPTLPPNQH

20.24

4.48

3.38

P32618

PVSYSPSNEP

15.35

-5.62

-6.72

DVPIVPGNNT

16.30

-2.15

-3.25

VGPKVPAKEP

17.56

-4.15

-5.25

Q03497

HKQHKPKVKP

14.84

-6.29

-7.39

IPSRPAPKPP

15.01

-9.05

-10.15

FIPSRPAPKP

16.36

-7.00

-8.10

P39969

RRAPKPPSYP

11.65

-6.95

-8.05

VSPRRAPKPP

13.29

-7.58

-8.68

LLPPQPGSKK

15.73

-5.43

-6.53

P22224

IFPSTPGTID

15.81

-7.58

-8.68

QSPMTPSTPT

21.06

-3.66

-4.76

SNGYQSPMTP

22.48

-6.46

-7.56

P35735

SPHFNPQSSE

22.44

-5.62

-6.72

ASPHFNPQSS

24.32

-3.45

-4.55

PHFNPQSSEK

24.63

-3.44

-4.54

 


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